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[患有生殖障碍的夫妇中的Q带染色体多态性]

[Q-band chromosome polymorphism in couples with reproductive disorders].

作者信息

Kruminia A R, Kroshkina V G, Reshetnikov A N

出版信息

Genetika. 1987 Mar;23(3):544-8.

PMID:3471678
Abstract

A comparative analysis of Q-band polymorphisms was conducted in phenotypically normal individuals and couples with repeated spontaneous abortions. In the group of pathology reduction of the following phenomena was found: frequencies of brilliant fluorescence in bands 4p11q11, 14p11, 14p13, 15p11, 21p13; the mean numbers of the brilliant fluorescent segments per cell per individual; frequencies of extremely large ("marker") Q-bands. All these findings coincided with our earlier published data on reduction of the C-heterochromatin amount in the same group of pathology.

摘要

对表型正常的个体和反复自然流产的夫妇进行了Q带多态性的比较分析。在病理组中发现了以下现象的减少:4p11q11、14p11、14p13、15p11、21p13带中亮荧光的频率;每个个体每个细胞中亮荧光片段的平均数;极大(“标记”)Q带的频率。所有这些发现与我们早期发表的关于同一病理组中C-异染色质数量减少的数据一致。

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