Bauer G E, Mitchell A S, Bates F, Hellestrand K
Med J Aust. 1977 Nov 26;2(22):733-5. doi: 10.5694/j.1326-5377.1977.tb99253.x.
A sustained-release preparation of procainamide (PAD) was evaluated in a double-blind cross-over study. The preparation was found to reduce ventricular ectopic activity in all seven patients who completed the investigation in five patients the effectiveness reached the defined level of significance. A larger clinical trial to assess the long-term use of this preparation in terms of efficacy, safety and convenience is recommended.
对普鲁卡因酰胺缓释制剂（PAD）进行了一项双盲交叉研究评估。结果发现，该制剂在完成研究的所有7例患者中均能降低室性异位活动，在5例患者中其有效性达到了规定的显著水平。建议开展一项更大规模的临床试验，以评估该制剂在疗效、安全性和便利性方面的长期使用情况。
