Decoration of titanium dioxide nanotubes with silver nanoparticles using the photochemical deposition method and their application as an electrocatalyst to determine tinidazole.

In this study, titanium nanotube electrodes were decorated with silver nanoparticles (AgNPs/TiONTs) and used as an electrocatalyst for the reduction of tinidazole. AgNPs/TiONTs are constructed by anodization of titanium sheet metal and photochemical deposition of AgNPs on TiONTs. The structural and elemental analysis characteristics of the AgNPs/TiONT electrode have been studied by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), and X-ray diffraction (XRD) methods. Based on the cyclic voltammetric data, it has been confirmed that the AgNPs/TiONT electrode has good electrocatalytic activity to reduce tinidazole. Two liner concentration ranges of 0.2-55.0 μM and 55.0-111.2 μM were obtained by amperometric method. A detection limit of 60.9 nM was obtained for measuring tinidazole at the AgNPs/TiONT electrode surface. In addition, the designed sensor has been successfully used for quantitative measurement of tinidazole in pharmaceutical and human urine samples.