Department of Chemistry, Faculty of Science, Yazd University, Yazd, 89195-741, Iran.
Anal Methods. 2021 Nov 18;13(44):5343-5350. doi: 10.1039/d1ay01179k.
In this study, titanium nanotube electrodes were decorated with silver nanoparticles (AgNPs/TiONTs) and used as an electrocatalyst for the reduction of tinidazole. AgNPs/TiONTs are constructed by anodization of titanium sheet metal and photochemical deposition of AgNPs on TiONTs. The structural and elemental analysis characteristics of the AgNPs/TiONT electrode have been studied by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), and X-ray diffraction (XRD) methods. Based on the cyclic voltammetric data, it has been confirmed that the AgNPs/TiONT electrode has good electrocatalytic activity to reduce tinidazole. Two liner concentration ranges of 0.2-55.0 μM and 55.0-111.2 μM were obtained by amperometric method. A detection limit of 60.9 nM was obtained for measuring tinidazole at the AgNPs/TiONT electrode surface. In addition, the designed sensor has been successfully used for quantitative measurement of tinidazole in pharmaceutical and human urine samples.
在这项研究中，钛纳米管电极被镀上了银纳米粒子（AgNPs/TiONTs），并被用作替硝唑还原的电催化剂。AgNPs/TiONTs 通过钛金属板的阳极氧化和 AgNPs 在 TiONTs 上的光化学沉积来构建。AgNPs/TiONT 电极的结构和元素分析特性已通过扫描电子显微镜 (SEM)、能谱 (EDS) 和 X 射线衍射 (XRD) 方法进行了研究。根据循环伏安数据，已证实 AgNPs/TiONT 电极对还原替硝唑具有良好的电催化活性。通过安培法获得了两个线性浓度范围，分别为 0.2-55.0 μM 和 55.0-111.2 μM。在 AgNPs/TiONT 电极表面测量替硝唑的检测限为 60.9 nM。此外，该设计的传感器已成功用于药物和人尿样中替硝唑的定量测量。
