Department of Preventive Medicine, Rush University Medical Center, Chicago, Illinois, USA.
Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.
Obesity (Silver Spring). 2022 Jan;30(1):45-49. doi: 10.1002/oby.23313. Epub 2021 Nov 23.
This study examined whether the efficacy of a standard-of-care pediatric obesity treatment was affected by the COVID-19 pandemic.
Analyses leveraged data from an ongoing pediatric obesity treatment trial involving 230 lower-income, urban children aged 6 to 12 years. Mixed-effects regression models compared children who participated in a 12-month weight-management intervention before versus during the COVID-19 pandemic on change from baseline in BMI z score (ΔzBMI) at 3, 6, 9, and 12 months.
The observed pattern of ΔzBMI was significantly different before versus during the pandemic (χ = 22.73, p < 0.0001). Children treated before the pandemic maintained an average weight loss of -0.06 ΔzBMI at 12 months, whereas children treated during the pandemic steadily gained weight over time, averaging a net gain of 0.11 ΔzBMI at 12 months (χ = 34.99, p < 0.0001). Treatment session completion did not differ before versus during the pandemic (60.4% vs. 55.7%, respectively; p = 0.30) or account for differences in ΔzBMI.
Similar reductions in intervention efficacy may be anticipated in other pediatric obesity treatment trials conducted during the COVID-19 pandemic. Many families that have struggled with managing their child's weight during this period may need encouragement to continue engaging in structured weight management as society renormalizes.
本研究旨在探讨在新冠疫情期间,标准的儿童肥胖治疗方法的疗效是否受到影响。
本研究利用一项正在进行的儿科肥胖治疗试验的数据进行分析,该试验涉及 230 名来自城市低收入家庭、年龄在 6 至 12 岁的儿童。混合效应回归模型比较了在新冠疫情之前和期间参加为期 12 个月的体重管理干预的儿童,在基线时 BMI z 分数(ΔzBMI)的变化,分别在 3、6、9 和 12 个月时进行比较。
ΔzBMI 的观察模式在疫情前后有显著差异(χ = 22.73,p < 0.0001)。在疫情之前接受治疗的儿童在 12 个月时平均体重减轻了-0.06 ΔzBMI,而在疫情期间接受治疗的儿童体重逐渐增加,在 12 个月时平均净增重 0.11 ΔzBMI(χ = 34.99,p < 0.0001)。在疫情前后,治疗疗程的完成率没有差异(分别为 60.4%和 55.7%;p = 0.30),也没有解释 ΔzBMI 的差异。
在新冠疫情期间进行的其他儿科肥胖治疗试验中,可能会预期到干预效果类似的降低。在这段时间里,许多家庭在管理孩子体重方面一直很困难,可能需要鼓励他们继续参与结构化的体重管理,因为社会正在恢复正常。