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儿童肥胖治疗在 COVID-19 大流行期间效果减弱。

Attenuated efficacy of pediatric obesity treatment during the COVID-19 pandemic.

机构信息

Department of Preventive Medicine, Rush University Medical Center, Chicago, Illinois, USA.

Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

Obesity (Silver Spring). 2022 Jan;30(1):45-49. doi: 10.1002/oby.23313. Epub 2021 Nov 23.

Abstract

OBJECTIVE

This study examined whether the efficacy of a standard-of-care pediatric obesity treatment was affected by the COVID-19 pandemic.

METHODS

Analyses leveraged data from an ongoing pediatric obesity treatment trial involving 230 lower-income, urban children aged 6 to 12 years. Mixed-effects regression models compared children who participated in a 12-month weight-management intervention before versus during the COVID-19 pandemic on change from baseline in BMI z score (ΔzBMI) at 3, 6, 9, and 12 months.

RESULTS

The observed pattern of ΔzBMI was significantly different before versus during the pandemic (χ = 22.73, p < 0.0001). Children treated before the pandemic maintained an average weight loss of -0.06 ΔzBMI at 12 months, whereas children treated during the pandemic steadily gained weight over time, averaging a net gain of 0.11 ΔzBMI at 12 months (χ = 34.99, p < 0.0001). Treatment session completion did not differ before versus during the pandemic (60.4% vs. 55.7%, respectively; p = 0.30) or account for differences in ΔzBMI.

CONCLUSIONS

Similar reductions in intervention efficacy may be anticipated in other pediatric obesity treatment trials conducted during the COVID-19 pandemic. Many families that have struggled with managing their child's weight during this period may need encouragement to continue engaging in structured weight management as society renormalizes.

摘要

目的

本研究旨在探讨在新冠疫情期间,标准的儿童肥胖治疗方法的疗效是否受到影响。

方法

本研究利用一项正在进行的儿科肥胖治疗试验的数据进行分析,该试验涉及 230 名来自城市低收入家庭、年龄在 6 至 12 岁的儿童。混合效应回归模型比较了在新冠疫情之前和期间参加为期 12 个月的体重管理干预的儿童,在基线时 BMI z 分数(ΔzBMI)的变化,分别在 3、6、9 和 12 个月时进行比较。

结果

ΔzBMI 的观察模式在疫情前后有显著差异(χ = 22.73,p < 0.0001)。在疫情之前接受治疗的儿童在 12 个月时平均体重减轻了-0.06 ΔzBMI,而在疫情期间接受治疗的儿童体重逐渐增加,在 12 个月时平均净增重 0.11 ΔzBMI(χ = 34.99,p < 0.0001)。在疫情前后,治疗疗程的完成率没有差异(分别为 60.4%和 55.7%;p = 0.30),也没有解释 ΔzBMI 的差异。

结论

在新冠疫情期间进行的其他儿科肥胖治疗试验中,可能会预期到干预效果类似的降低。在这段时间里,许多家庭在管理孩子体重方面一直很困难,可能需要鼓励他们继续参与结构化的体重管理,因为社会正在恢复正常。

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