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颞骨腺瘤:对一种极为罕见疾病的临床特征及手术结果的综合分析

Temporal Bone Adenoma: A Comprehensive Analysis of Clinical Aspects and Surgical Outcome on a Very Rare Entity.

作者信息

Alsalman Hussain, Crowther John A, McLellan Douglas, Kontorinis Georgios

机构信息

Department of Otorhinolaryngology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.

Medical School, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Neurol Surg B Skull Base. 2020 Oct 5;82(6):638-642. doi: 10.1055/s-0040-1715812. eCollection 2021 Dec.

Abstract

The aim of this study is to present our experience in dealing with middle ear adenomas (MEAs), very rare tumors of the middle ear.  The medical notes of individuals with MEAs treated in tertiary referral; academic settings were retrospectively reviewed. We recorded the presenting symptoms, imaging findings, and pathology results. We additionally examined our surgical outcomes, follow-up period, recurrence, and morbidity.  We identified four patients with MEAs: two males and two females with an average age of 36.25 years (range = 27-51 years). Despite the detailed imaging studies, including computed tomography and magnetic resonance imaging with intravenous contrast administration, a biopsy was essential in setting the diagnosis. Total surgical resection was achieved in all patients without any recurrence over an average of 6 years (range = 3-10 years). Complete ipsilateral deafness was the commonest surgical morbidity due to footplate infiltration by the tumor.  Total surgical resection is the treatment of choice in MEAs to minimize the risk for recurrence; this can come with morbidity, mostly sensorineural deafness. Given the very limited literature, long-term follow-up is recommended.

摘要

本研究的目的是介绍我们处理中耳腺瘤(MEA)的经验,中耳腺瘤是一种非常罕见的中耳肿瘤。 回顾性分析了在三级转诊学术机构接受治疗的MEA患者的病历。我们记录了患者的症状、影像学检查结果和病理结果。此外,我们还检查了手术结果、随访期、复发情况和发病率。 我们确定了4例MEA患者:2例男性和2例女性,平均年龄36.25岁(范围为27-51岁)。尽管进行了包括计算机断层扫描和静脉注射造影剂的磁共振成像在内的详细影像学检查,但活检对于明确诊断至关重要。所有患者均实现了手术全切,平均6年(范围为3-10年)内无复发。由于肿瘤侵犯镫骨底板,同侧完全性耳聋是最常见的手术并发症。 手术全切是MEA的首选治疗方法,以降低复发风险;这可能会带来并发症,主要是感音神经性耳聋。鉴于相关文献非常有限,建议进行长期随访。

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[Middle ear adenoma/middle ear carcinoid--an unproblematic tumor?].[中耳腺瘤/中耳类癌——一种无问题的肿瘤?]
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