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[正电子发射断层扫描-计算机断层扫描(PET-CT)在大血管血管炎诊断中的应用]

[Positron emission tomography-CT scan (PET-CT) in the diagnosis of large vessel vasculitis].

作者信息

Vicentela I Andrés, Cifuentes J Camila, Barahona Z Daniela, Chong M Guillermo, Schiappacasse F Giancarlo

机构信息

Departamento de Imágenes, Facultad de Medicina Clínica Alemana de Santiago-Universidad del Desarrollo, Santiago, Chile.

Departamento de Imágenes, Facultad de Medicina Clínica Alemana-Universidad del Desarrollo, Santiago, Chile.

出版信息

Rev Med Chil. 2021 May;149(5):773-778. doi: 10.4067/s0034-98872021000500773.

Abstract

Vasculitides are a broad group of diseases that can involve any kind of vessel in any organ. These can be classified according to the size of the affected vessels. The most used classification categorizes them in small, medium, and large vessel vasculitis. Large vessel vasculitis can be further divided in Takayasu arteritis and giant cell arteritis which can sometimes be indistinguishable, even with biopsy. Radiology plays an important role identifying distribution patterns and disease extension18. Fluorine-Fluorodeoxyglucose (FDG) PET-CT shows increased vessel wall FDG uptake in patients with active large vessel vasculitis. Multiple studies show that FDG PET-CT helps to identify the anatomic structures with the disease, as well as evaluate its progression with a high sensibility and specificity in non-treated patients with large vessel vasculitis.

摘要

血管炎是一大类疾病,可累及任何器官中的任何类型血管。这些疾病可根据受累血管的大小进行分类。最常用的分类方法将它们分为小血管、中血管和大血管血管炎。大血管血管炎可进一步分为高安动脉炎和巨细胞动脉炎,有时即使通过活检也难以区分。放射学在识别分布模式和疾病范围方面发挥着重要作用。氟脱氧葡萄糖(FDG)PET-CT显示活动性大血管血管炎患者血管壁FDG摄取增加。多项研究表明,FDG PET-CT有助于识别患有该疾病的解剖结构,并在未经治疗的大血管血管炎患者中以高敏感性和特异性评估其进展情况。

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