Department of Gastroenterology, Meizhou People's Hospital, Meizhou, China.
Ann Palliat Med. 2021 Oct;10(10):10963-10970. doi: 10.21037/apm-21-2648.
Among patients with a benign stricture in the upper gastrointestinal tract, those with esophagogastric anastomosis stricture (EAS) due to complications after esophagectomy for esophageal carcinoma comprise the majority. Dilation is the primary surgical treatment for EAS, but its short-term effect is not remarkable and its long-term effect is worse.
We compared endoscopic radial incision (ERI) and Savary-Gilliard's bougie dilation (SGBD) for patients with refractory EAS, and evaluated overall efficacy and complications. Stooler's scale was used to grade the patients' dysphagia before surgery. The two groups were compared for the number of dilations or incisions, the degree of dilation of the EAS after surgery and postoperative complications, such as intraoperative bleeding (arteriopalmus bleeding requiring endoscopic intervention), postoperative bleeding (hematemesis, bloody stool or black stool), postoperative perforation (fistula formation confirmed by gastrointestinal radiography), and postoperative infection (including postoperative fever).
The Exp group had 15 markedly effectively treated patients, 7 effectively treated patients, and 3 ineffectively treated patients, while the numbers of these patients in the Obs group were 5, 6, and 10, respectively. Thus, the Exp group had a significantly higher total effective rate than the Obs group (88.0% vs. 52.4%, P<0.05). Patients treated by ERI had higher overall therapeutic effect, better swallowing symptom grade, and lower incidence of complications.
Thus, ERI is superior to SGBD in efficacy and safety for treating refractory EAS.
在上消化道良性狭窄患者中,因食管癌手术后并发症而导致的食管胃吻合口狭窄(EAS)占大多数。扩张是 EAS 的主要手术治疗方法,但短期效果不明显,长期效果更差。
我们比较了内镜下放射状切开术(ERI)和 Savary-Gilliard 探条扩张术(SGBD)治疗难治性 EAS 的效果,并评估了总体疗效和并发症。术前采用 Stooler 量表对患者吞咽困难程度进行分级。比较两组患者的扩张或切开次数、EAS 术后扩张程度以及术中出血(需要内镜干预的动脉搏动性出血)、术后出血(呕血、血便或黑便)、术后穿孔(胃肠造影证实瘘形成)和术后感染(包括术后发热)等并发症。
Exp 组 15 例患者治疗效果显著,7 例有效,3 例无效;Obs 组分别为 5、6、10 例。因此,Exp 组的总有效率明显高于 Obs 组(88.0%比 52.4%,P<0.05)。ERI 治疗患者的总体疗效更高,吞咽症状分级更好,并发症发生率更低。
因此,ERI 在治疗难治性 EAS 的疗效和安全性方面优于 SGBD。