Clinique Du Souffle La Vallonie - Korian, Lodève, France; Euromov Digital Health in Motion, University of Montpellier, IMT Mines Ales, Montpellier, France; Direction de La Recherche Clinique et de L'innovation en Santé - Korian, Lodève, France; GCS CIPS, Lodève, France.
Direction de La Recherche Clinique et de L'innovation en Santé - Korian, Lodève, France; GCS CIPS, Lodève, France.
Respir Med. 2021 Dec;190:106680. doi: 10.1016/j.rmed.2021.106680. Epub 2021 Nov 5.
The effectiveness of pulmonary rehabilitation (PR) is a critical issue for chronic obstructive pulmonary disease (COPD) patients. However, PR response is marked by a strong heterogeneity, partially unexplained to date. We hypothesized that personality traits defined by the Five-Factor Model could modulate the effect of inpatient-PR.
The aim was to assess the associations between these five personality traits and PR outcomes.
74 persons with COPD admitted for a 5-week inpatient PR program had a personality assessment at the start of the program (T1). Exercise capacity, quality of life, sensory and affective dyspnea dimensions were assessed at T1 and at the end of the program (T2). Their evolution was evaluated using the delta score between T2 and T1. PR response was defined using the minimal clinically important change score for each of them. A composite response was established distinguishing the poor responders' group, made of patients who responded to 0, 1 or 2 parameters and the good responders' group, with patients who responded on 3 or 4 indicators.
Logistic regressions analyses highlighted that those with a high level of openness [OR = 0.36, 95% CI = 0.15-0.74, p < 0.01] were less likely to respond on quality of life, controlling for socio-demographic factors and the severity of the disease.
This study shows that the investigation of the personality constitutes an interesting perspective for better understanding the interindividual differences observed between patients in the PR response. Tailoring clinical intervention to the patient's personality could be a promising prospect for optimizing PR effectiveness.
肺康复（PR）的效果是慢性阻塞性肺疾病（COPD）患者的一个关键问题。然而，PR 的反应具有很强的异质性，目前部分原因尚未得到解释。我们假设，五因素模型定义的人格特质可以调节住院 PR 的效果。
评估这些五种人格特质与 PR 结果之间的关系。
74 名 COPD 患者接受了为期 5 周的住院 PR 计划，在计划开始时（T1）进行了人格评估。在 T1 和计划结束时（T2）评估了运动能力、生活质量、感觉和情感呼吸困难维度。使用 T2 与 T1 之间的差值评分评估其演变。使用每个参数的最小临床重要变化评分来定义 PR 反应。通过区分仅对 0、1 或 2 个参数有反应的差反应者组和对 3 或 4 个指标有反应的好反应者组来建立复合反应。
逻辑回归分析表明，那些具有高水平开放性的人[OR=0.36，95%CI=0.15-0.74，p<0.01]更不可能对生活质量有反应，这控制了社会人口因素和疾病的严重程度。
这项研究表明，对人格的研究为更好地理解 PR 反应中患者之间观察到的个体差异提供了一个有趣的视角。根据患者的人格特质调整临床干预可能是优化 PR 效果的一个有前途的前景。
