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验证肾移植后淋巴并发症的共识定义严重程度分级

Validating Consensus-Defined Severity Grading of Lymphatic Complications after Kidney Transplant.

作者信息

Sabagh Mohammadsadegh, Mohammadi Sara, Ramouz Ali, Khajeh Elias, Ghamarnejad Omid, Morath Christian, Mieth Markus, Kulu Yakup, Zeier Martin, Mehrabi Arianeb, Golriz Mohammad

机构信息

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.

Department of Nephrology, Heidelberg University Hospital, 69120 Heidelberg, Germany.

出版信息

J Clin Med. 2021 Oct 22;10(21):4858. doi: 10.3390/jcm10214858.

Abstract

Lymphatic complications after kidney transplantation (KTx) are associated with morbidities such as impaired wound healing, thrombosis, and organ failure. Recently, a consensus regarding the definition and severity grading of lymphoceles has been suggested. The aim of the present study was to validate this classification method. All adult patients who underwent KTx between December 2011 and September 2016 in our department were evaluated regarding lymphoceles that were diagnosed within 6 months after KTx based on the recent definition. Patients with lymphoceles were categorized according to the classification criteria, and clinical outcomes were compared between the groups. In our department, a total of 587 patients underwent KTx between 2011 and 2016. Lymphoceles were detected after KTx in 90 patients (15.3%). Among these patients, 24 (26.6%) had grade A lymphoceles, 14 (15.6%) had grade B, and 52 (57.8%) had grade C. The median duration times of intermediate care (IMC) and hospital stay were significantly higher among patients with grade C lymphoceles than they were among patients with grade A and B lymphoceles. Significantly more patients with grade C lymphoceles were readmitted to the hospital for treatment. The recently published definition and severity grading of lymphoceles after KTx is an easy-to-use and valid classification system, which may facilitate the comparison of results from different studies on lymphoceles after KTx.

摘要

肾移植(KTx)后的淋巴并发症与诸如伤口愈合受损、血栓形成和器官衰竭等病症相关。最近,有人提出了关于淋巴管瘤的定义和严重程度分级的共识。本研究的目的是验证这种分类方法。对2011年12月至2016年9月在我科接受KTx的所有成年患者进行评估,这些患者根据最新定义在KTx后6个月内被诊断为淋巴管瘤。将患有淋巴管瘤的患者按照分类标准进行分类,并比较各组之间的临床结果。在我科,2011年至2016年间共有587例患者接受了KTx。90例患者(15.3%)在KTx后检测到淋巴管瘤。在这些患者中,24例(26.6%)为A级淋巴管瘤,14例(15.6%)为B级,52例(57.8%)为C级。C级淋巴管瘤患者的中间护理(IMC)和住院时间中位数显著高于A级和B级淋巴管瘤患者。C级淋巴管瘤患者再次入院治疗的人数明显更多。最近发表的KTx后淋巴管瘤的定义和严重程度分级是一个易于使用且有效的分类系统,这可能有助于比较不同研究关于KTx后淋巴管瘤结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9b1/8584504/d79b84cf7782/jcm-10-04858-g001.jpg

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