Center for Graduate Medical Education, Okayama University Hospital, Japan.
Department of Emergency, Critical Care, and Disaster Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.
Intern Med. 2022 Jun 15;61(12):1913-1916. doi: 10.2169/internalmedicine.8409-21. Epub 2021 Nov 13.
Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.
长期维生素 C 缺乏可导致多种代谢异常,如组织修复受损和胶原合成缺陷。本病例报告描述了一位中年日本男性,其下肢出现疼痛性紫癜、严重贫血和意识改变。该患者自童年起就一直采用选择性饮食,缺乏蔬菜和水果。血清分析显示维生素 C 水平较低。患者接受了维生素补充和心理干预。坏血病是一种被低估的疾病,如果早期诊断且病情仍处于早期,预后良好,但即使在现代,一些吸收不良或营养不良的患者仍会偶尔发生坏血病。