In this paper, sulfated ZrO were synthesized via precipitation and impregnation method, and the promoting effects of support sulfation on selective catalytic reduction (SCR) performance of CeO/ZrO catalysts were investigated. The results revealed that sulfated ZrO could significantly enhance the SCR activity of CeO/ZrO catalysts in a wide temperature range. Especially when S/Zr molar ratio was 0.1, CeO/ZrO-0.1S catalyst exhibited a large operating temperature window of 251 ∼ 500 °C and its N selectivity was 100 % in the temperature range of 150 ∼ 500 °C. Moreover, CeO/ZrO-0.1S catalyst possessed a superior low-temperature activity over 0.1S-CeO/ZrO catalyst. After exposing to 100 ppm SO for 15 h, a high NO conversion efficiency of CeO/ZrO-0.1S catalyst (90.7 %) could still be reached. The characterization results indicated that ZrO treated with a proper dosage of sulfate acid was beneficial to enlarge the specific surface area greatly. Sulfated ZrO was also in favor of promoting the transformation of CeO from crystalline state to highly-dispersed amorphous state, and inhibiting the transformation of ZrO from tetragonal to monoclinic phase. It could also enhance the total surface acidity greatly with an increase in both Brønsted acid sites and Lewis acid sites, thus significantly improving NH adsorption on catalyst surface. Besides, the promoting effect of support sulfation on SCR performance of CeO/ZrO catalysts was also related with the enhanced redox property, higher Ce/(Ce+Ce) ratio and abundant surface chemisorbed labile oxygen. The in-situ DRIFTS results implied that nitrate species coordinated on the surface of CeO/ZrO-0.1S catalyst could participate in the Selective catalytic reduction with ammonia (NH-SCR) reactions at either medium or high temperature, suggesting that both Eley-Rideal (E-R) and Langmuir-Hinshelwood (L-H) mechanisms might be followed in SCR reactions.