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痴呆或谵妄住院患者的抗精神病药物处方

Antipsychotic prescribing in people admitted to hospital with dementia or delirium.

作者信息

Tumusiime William A, Hardman Caitlin J, Breen Juanita L

机构信息

Ipswich Hospital, Ipswich, Queensland, Australia.

School of Pharmacy, University of Queensland, St. Lucia, Queensland, Australia.

出版信息

Australas J Ageing. 2022 Jun;41(2):258-264. doi: 10.1111/ajag.13017. Epub 2021 Nov 18.

Abstract

OBJECTIVE

To evaluate antipsychotic prescribing in people with dementia or delirium admitted to a large regional Queensland hospital.

METHODS

A retrospective observational study analysing medical records of patients prescribed antipsychotics over 6 months.

RESULTS

We audited a sample of 141 patients, 65 years or over (over 45 years for indigenous peoples) with dementia or delirium, without severe mental illness, prescribed antipsychotics. Over a third (35%) were prescribed antipsychotics prior to admission, with 73% prescribed a new antipsychotic in hospital. Only 23% received documented review of antipsychotic therapy. Under half (48%) had evidence of non-pharmacological interventions as first-line management. Sixty-eight patients (48%) were discharged with antipsychotics; however, only 4% were provided an antipsychotic management plan.

CONCLUSIONS

Initiation and continuation of antipsychotics in patients with dementia or delirium in hospital is common, with infrequent review. There is significant potential to reduce prescribing antipsychotics in people admitted to hospital with dementia or delirium.

摘要

目的

评估昆士兰州一家大型地区医院收治的痴呆或谵妄患者的抗精神病药物处方情况。

方法

一项回顾性观察研究,分析6个月内开具抗精神病药物的患者的病历。

结果

我们审核了141例65岁及以上(原住民为45岁以上)患有痴呆或谵妄、无严重精神疾病且开具了抗精神病药物的患者样本。超过三分之一(35%)的患者在入院前就已开具抗精神病药物,73%的患者在住院期间开具了新的抗精神病药物。只有23%的患者接受了抗精神病药物治疗的书面评估。不到一半(48%)的患者有非药物干预作为一线治疗的证据。68名患者(48%)出院时仍在使用抗精神病药物;然而,只有4%的患者获得了抗精神病药物管理计划。

结论

在医院中,痴呆或谵妄患者启动和持续使用抗精神病药物的情况很常见,但评估较少。在收治痴呆或谵妄患者的医院中,减少抗精神病药物处方有很大潜力。

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