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2015-2018 年加拿大安大略省省级监狱中阿片类激动剂治疗处方率:一项重复横断面分析。

Rates of opioid agonist treatment prescribing in provincial prisons in Ontario, Canada, 2015-2018: a repeated cross-sectional analysis.

机构信息

Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

出版信息

BMJ Open. 2021 Nov 18;11(11):e048944. doi: 10.1136/bmjopen-2021-048944.

Abstract

OBJECTIVE

To describe opioid agonist treatment prescribing rates in provincial prisons and compare with community prescribing rates.

DESIGN

We used quarterly, cross-sectional data on the number and proportion of people prescribed opioid agonist treatment in prison populations. Trends were compared with Ontario surveillance data from prescribers, reported on a monthly basis.

SETTING

Provincial prisons and general population in Ontario, Canada between 2015 and 2018.

PARTICIPANTS

Adults incarcerated in provincial prisons and people ages 15 years and older in Ontario.

MAIN OUTCOMES AND MEASURES

Opioid agonist treatment prescribing prevalence, defined as treatment with methadone or buprenorphine/naloxone.

RESULTS

In prison, 6.9%-8.4% of people were prescribed methadone; 0.8% to 4.8% buprenorphine/naloxone; and 8.2% to 13.2% either treatment over the study period. Between 2015 and 2018, methadone prescribing prevalence did not substantially change in prisons or in the general population. The prevalence rate of buprenorphine/naloxone prescribing increased in prisons by 1.70 times per year (95% CI 1.47 to 1.96), which was significantly higher than the increase in community prescribing: 1.20 (95% CI 1.19 to 1.21). Buprenorphine/naloxone prescribing prevalence was significantly different across prisons.

CONCLUSIONS

The increase in opioid agonist treatment prescribing between 2015 and 2018 in provincial prisons shows that efforts to scale up access to treatment in the context of the opioid overdose crisis have included people who experience incarceration in Ontario. Further work is needed to understand unmet need for treatment and treatment impacts.

摘要

目的

描述省级监狱中阿片类激动剂治疗的处方率,并与社区处方率进行比较。

设计

我们使用了关于监狱人群中阿片类激动剂治疗人数和比例的季度横断面数据。趋势与每月报告的安大略省处方医生的监测数据进行了比较。

设置

加拿大安大略省的省级监狱和一般人群,时间范围为 2015 年至 2018 年。

参与者

在省级监狱中被监禁的成年人以及安大略省 15 岁及以上的人群。

主要结果和措施

阿片类激动剂治疗的处方流行率,定义为使用美沙酮或丁丙诺啡/纳洛酮进行的治疗。

结果

在监狱中,6.9%-8.4%的人被开美沙酮处方;0.8%-4.8%的人开丁丙诺啡/纳洛酮处方;在研究期间,8.2%-13.2%的人接受了两种治疗。2015 年至 2018 年期间,监狱和普通人群中美沙酮处方的流行率没有实质性变化。丁丙诺啡/纳洛酮在监狱中的处方率每年增加 1.70 倍(95%CI 1.47 至 1.96),明显高于社区处方的增长率:1.20(95%CI 1.19 至 1.21)。丁丙诺啡/纳洛酮的处方率在不同监狱之间存在显著差异。

结论

2015 年至 2018 年期间,省级监狱中阿片类激动剂治疗的处方率增加表明,在阿片类药物过量危机背景下,扩大治疗机会的努力包括了在安大略省经历监禁的人群。需要进一步努力了解未满足的治疗需求和治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21fa/8603292/cfd5cba606d8/bmjopen-2021-048944f01.jpg

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