Xing Yuan-Yuan, Xue Hong-Yuan, Ye Yu-Quan
Hebei Medical University, Shijiazhuang, Hebei, 050017, People's Republic of China.
Department of Ultrasound, Hebei General Hospital, Shijiazhuang, 050051, Hebei, People's Republic of China.
Int J Gen Med. 2021 Nov 9;14:7971-7981. doi: 10.2147/IJGM.S332855. eCollection 2021.
This study aims to explore the feasibility of HeartModel (HM) three-dimensional echocardiography (3DE) to assess left ventricular function and discover suitable border parameter settings.
A total of 113 patients that underwent echocardiography in our hospital were eligible for inclusion. The HM 3DE (HM method) and conventional 3DE (3D method) were used to analyze echocardiography images. The HM was set to different border settings (end-diastolic [ED] and end-systolic [ES] settings) to assess different left ventricular systolic function parameters including left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), and left ventricular ejection fraction (LVEF), and left ventricular diastolic function parameters including maximal left atrium volume (LAV). All of these parameters were evaluated using the HM method and then compared with the 3D method.
The differences in LVEDV, LVESV, and LVEF measured with different HM border settings were statistically significant (P<0.05) and were strongly correlated with the 3D method. For LVEF, the reading using the HM method with ED and ES = 70 and 30 showed the best agreement with the 3D method, and the difference in the readings was not statistically significant (P > 0.05). For LVEDV and LVESV, the reading using the HM method with ED and ES = 40 and 20 showed the best agreement with the 3D method, but the difference in the readings was statistically significant (P < 0.05). The measurements taken using the HM method were more reproducible than those taken using the 3D method (P<0.05). The measurement time when using the HM method was significantly less than the 3D method (P<0.05). In terms of LAV, the correlation between the HM and 3D methods was strong, but the requirements for agreement were not satisfied.
Evaluation of the left ventricular function using HM 3DE is feasible, saves time, and is reproducible. To assess the left ventricular function, the border parameter setting of ED and ES = 70 and 30 provided the best fit for the Chinese population.
本研究旨在探讨心脏模型(HM)三维超声心动图(3DE)评估左心室功能及发现合适边界参数设置的可行性。
共有113例在我院接受超声心动图检查的患者符合纳入标准。采用HM 3DE(HM法)和传统3DE(3D法)分析超声心动图图像。将HM设置为不同的边界设置(舒张末期[ED]和收缩末期[ES]设置),以评估不同的左心室收缩功能参数,包括左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)和左心室射血分数(LVEF),以及左心室舒张功能参数,包括最大左心房容积(LAV)。所有这些参数均采用HM法进行评估,然后与3D法进行比较。
不同HM边界设置测量的LVEDV、LVESV和LVEF差异有统计学意义(P<0.05),且与3D法高度相关。对于LVEF,采用ED和ES = 70和30的HM法读数与3D法一致性最佳,读数差异无统计学意义(P>0.05)。对于LVEDV和LVESV,采用ED和ES = 40和20的HM法读数与3D法一致性最佳,但读数差异有统计学意义(P<0.05)。采用HM法进行的测量比采用3D法进行的测量更具可重复性(P<0.05)。使用HM法的测量时间明显少于3D法(P<0.05)。就LAV而言,HM法与3D法之间相关性较强,但未满足一致性要求。
使用HM 3DE评估左心室功能是可行的,省时且具有可重复性。为评估左心室功能,ED和ES = 70和30的边界参数设置最适合中国人群。