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胃化生及其向胃腺癌的快速进展:呼吁明确患者管理并提高认识。

Gastric Intestinal Metaplasia and Its Rapid Progression Toward Gastric Adenocarcinoma: A Call for Clear Patient Management and Awareness.

作者信息

Al Hennawi Hussam, Khedr Anwar, Maan Ramanpreet K, Albarazi Mohieddin, Atluri Purna

机构信息

Internal Medicine, Alfaisal University College of Medicine, Riyadh, SAU.

Internal Medicine, Tanta University Faculty of Medicine, Tanta, EGY.

出版信息

Cureus. 2021 Oct 13;13(10):e18751. doi: 10.7759/cureus.18751. eCollection 2021 Oct.

Abstract

Gastric cancer is one of the leading causes of cancer-related death worldwide. () infection is known to cause gastric adenocarcinoma in a stepwise fashion. Gastric intestinal metaplasia is a known premalignant stage. We report a case of a 70-year-old male patient with active chronic associated gastritis and focal intestinal metaplasia on the initial presentation, who rapidly developed diffuse, poorly differentiated gastric adenocarcinoma 20 months after the loss to follow-up. Our case highlights the premalignant nature of gastric intestinal metaplasia (GIM) and the extreme importance of early eradication of . We also address the lack of definitive GIM surveillance guidelines.

摘要

胃癌是全球癌症相关死亡的主要原因之一。已知()感染会逐步导致胃腺癌。胃肠化生是一个已知的癌前阶段。我们报告一例70岁男性患者,初诊时患有活动性慢性相关性胃炎和局灶性肠化生,在失访20个月后迅速发展为弥漫性、低分化胃腺癌。我们的病例突出了胃肠化生(GIM)的癌前性质以及早期根除()的极端重要性。我们还讨论了缺乏明确的GIM监测指南的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4ad/8589342/0b9dd377398f/cureus-0013-00000018751-i01.jpg

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