儿童牙髓治疗后恒牙的存活率：回顾性队列研究。
Survival of endodontically treated permanent teeth among children: a retrospective cohort study.
机构信息
Department of Endodontics, Boston University Henry M Goldman School of Dental Medicine, 635 Albany St, G200, Boston, MA, 02118, USA.
University of Detroit Mercy School of Dentistry, Detroit, MI, USA.
出版信息
BMC Oral Health. 2021 Nov 19;21(1):589. doi: 10.1186/s12903-021-01952-y.
BACKGROUND
Outcome studies of nonsurgical root canal treatment (NSRCT) in permanent teeth of children are scarce. This study investigated survival and assessed the variables associated with failure of endodontically treated teeth (ETT) in 6- to 18-year-olds.
METHODS
Records of subjects who received NSRCT at age 6-18 years at Boston University between 2007 and 2015 were assessed for the occurrence of untoward events. Kaplan-Meier survival curves were used to investigate the survival of ETT in the total sample. Adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) were estimated.
RESULTS
The analysis included 341 patients (424 ETT). Kaplan-Meier survival curves differed according to age at treatment (log-rank P = 0.026), with survival being the lowest among the youngest age group. The estimated 5-year survival probability was 80% for 15- to 18-year-olds, 64.8% for 12- to 14-year-olds and 46.4% for 6- to 11-year-olds. Compared to age at treatment of 15-18 years, age at treatment of 6-11 years (aHR: 2.19, 95% CI 1.02-4.67) and 12-14 years (aHR: 2.02, 95% CI 1.15-3.55) was associated with an increased risk of ETT failure. In the total study sample, the estimated cumulative survival probability was 93.3% at 12 months, 88.0% at 24 months, 76.2% at 36 months, 71.0% at 48 months, and 69.1% at 60 months.
CONCLUSIONS
In children, ETT are more likely to survive when NSRCTs are performed at an older age.
背景
儿童非手术根管治疗（NSRCT）的疗效研究很少。本研究调查了 6 至 18 岁儿童接受根管治疗的牙齿（ETT）的生存率，并评估了与治疗失败相关的变量。
方法
评估了 2007 年至 2015 年期间在波士顿大学接受 NSRCT 的 6 至 18 岁患者的记录，以调查不良事件的发生情况。Kaplan-Meier 生存曲线用于研究总样本中 ETT 的生存率。估计了调整后的风险比（aHR）和 95%置信区间（CI）。
结果
该分析纳入了 341 名患者（424 颗 ETT）。Kaplan-Meier 生存曲线因治疗时的年龄而异（对数秩 P=0.026），年龄最小的组的生存率最低。估计 15 至 18 岁患者的 5 年生存率为 80%，12 至 14 岁患者为 64.8%，6 至 11 岁患者为 46.4%。与 15-18 岁时的治疗年龄相比，6-11 岁（aHR：2.19，95%CI 1.02-4.67）和 12-14 岁（aHR：2.02，95%CI 1.15-3.55）时的治疗年龄与 ETT 失败的风险增加相关。在总研究样本中，12 个月时的估计累积生存率为 93.3%，24 个月时为 88.0%，36 个月时为 76.2%，48 个月时为 71.0%，60 个月时为 69.1%。
结论
在儿童中，NSRCT 治疗时年龄较大，ETT 更有可能存活。
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