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内镜减重术治疗慢性肝病患者

Endoscopic Bariatric Interventions in Patients with Chronic Liver Disease.

机构信息

Division of Gastroenterology and Hepatology, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA.

Division of Gastroenterology and Hepatology, Texas Tech University Health Sciences Center, 4800 Alberta Avenue, El Paso, TX 79905, USA.

出版信息

Clin Liver Dis. 2022 Feb;26(1):139-148. doi: 10.1016/j.cld.2021.08.005. Epub 2021 Sep 16.

Abstract

Obesity and its associated comorbidities are rapidly increasing in the US population. Therefore, metabolic associated fatty liver disease (MAFLD), previously known as nonalcoholic fatty liver disease (NAFLD), has become a leading indication for liver transplantation. Lifestyle modifications as a sole therapy have been insufficient to reduce the burden of chronic liver disease secondary to MAFLD. Endoscopic bariatric interventions (EBI) appear to be safe and effective therapies for obesity and chronic liver disease secondary to MAFLD. Gastric EBI include endoscopic sleeve gastroplasty (ESG) and intragastric balloons (IGB). Small bowel EBI are also evolving in the field of bariatric endoscopy.

摘要

在美国人群中,肥胖及其相关合并症正在迅速增加。因此,代谢相关脂肪性肝病(MAFLD),以前称为非酒精性脂肪性肝病(NAFLD),已成为肝移植的主要指征。作为单一疗法的生活方式改变不足以减轻 MAFLD 引起的慢性肝病负担。内镜减重干预(EBI)似乎是肥胖和 MAFLD 引起的慢性肝病的安全有效的治疗方法。胃 EBI 包括内镜袖状胃成形术(ESG)和胃内球囊(IGB)。小肠 EBI 在减重内镜领域也在不断发展。

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