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美国各州与欧洲国家之间的器官捐赠与移植差异:选择退出是否有益?

Differences in Organ Donation and Transplantation in States Within the United States and in European Countries: Is There a Benefit to Opting Out?

机构信息

Department of Cardiovascular & Thoracic Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States.

Department of Cardiovascular & Thoracic Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas, United States.

出版信息

Transplant Proc. 2021 Dec;53(10):2801-2806. doi: 10.1016/j.transproceed.2021.09.029. Epub 2021 Nov 19.

Abstract

BACKGROUND

Organ donation in the United States currently requires explicit consent by an "opt-in" approach. Some European countries have reported an increase in donation rates with an "opt-out" strategy. We hypothesized that regional differences in decision making affect organ donation rates in different countries and suggest no single approach will reliably increase organ donation rates.

METHODS

Donation and transplantation rates in European countries and states within the United States with populations of >10 million and a minimum organ donation rate of 10 donors per million were compared. 2016 International Registry in Organ Donation and Transplantation data and the 2016 Scientific Registry of Transplant Recipients annual report were used for European countries and US states, respectively. Comparisons by region and donation model were made.

RESULTS

Deceased organ donor rates and transplants did not differ between opt-in and opt-out models. Living donation was increased in all opt-in entities. When comparing European countries, there was a trend toward higher organ donation rates in opt-out countries than in opt-in countries. Donation and transplantation rates of US states were higher than both European opt-in and opt-out countries.

CONCLUSION

There were no differences in deceased donor organ donation when considering the donation consent model. These data do not support that an opt-out approach will increase the number of transplants in the United States.

摘要

背景

目前,美国的器官捐赠需要通过“选择加入”的方式获得明确同意。一些欧洲国家报告称,采用“选择退出”策略后,捐赠率有所上升。我们假设,不同国家在决策方面的差异会影响器官捐赠率,而且没有单一的方法能够可靠地提高器官捐赠率。

方法

比较了 2016 年国际器官捐赠和移植登记处的数据以及 2016 年科学移植受者年度报告中,欧洲国家和美国人口超过 1000 万且每百万人口器官捐献率至少为 10 人的州的捐赠和移植率。对欧洲国家和美国各州分别采用了 2016 年国际器官捐赠和移植登记处的数据和 2016 年科学移植受者年度报告。比较了不同地区和捐赠模式的情况。

结果

选择加入和选择退出模型之间,脑死亡器官捐献者的比例和移植数量没有差异。所有选择加入的实体中,活体捐献都有所增加。在比较欧洲国家时,选择退出的国家的器官捐赠率呈上升趋势,高于选择加入的国家。美国各州的捐赠和移植率均高于欧洲的选择加入和选择退出国家。

结论

考虑到捐赠同意模式,脑死亡器官捐赠者的器官捐赠没有差异。这些数据不支持美国采用选择退出的方法会增加移植数量。

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