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胸大肌前乳房重建:双侧降低风险乳房切除术的理想方法。

Prepectoral breast reconstruction: an ideal approach to bilateral risk-reducing mastectomy.

作者信息

Maruccia Michele, Elia Rossella, Tedeschi Pasquale, Gurrado Angela, Moschetta Marco, Testini Mario, Giudice Giuseppe

机构信息

Division of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Piazza Giulio Cesare, Bari, Italy.

Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Piazza Giulio Cesare, Bari, Italy.

出版信息

Gland Surg. 2021 Oct;10(10):2997-3006. doi: 10.21037/gs-21-339.

Abstract

BACKGROUND

Bilateral risk-reducing mastectomy (BRRM) has increased its popularity in the last years because of its aim to minimise the chances of developing breast cancer in high-risk patients. Women undergoing this procedure must be considered highly demanding patients given the need to combine aesthetical, functional and preventive desires. This study aims to present the authors' experience in performing BRRM followed by single-stage prepectoral reconstruction (PPBR) with implant completely covered by acellular dermal matrix (ADM) and to report indications, surgical techniques, functional and aesthetic results.

METHODS

A single-centre prospective data collection was carried out from January 2017 to January 2021 of patients at high risk of developing breast cancer undergoing BRRM and immediate PPBR with ADM. Patients were subdivided into two groups according to the breast shape: Group A had small and medium size breasts and Group B had large and ptotic breasts. Oncological and surgical outcomes were collected. Satisfaction with reconstruction and related quality of life were evaluated through the BREAST-Q questionnaire.

RESULTS

A total of twenty-three patients met the inclusion criteria. Seventeen patients were included in group A and six patients in group B. Average follow-up was 18.4 months. Minor complications occurred in four breasts: one seroma, one hematoma and two cases of wound dehiscence. Capsular contracture was not observed. All patients were satisfied with the final result according to the post-operative BREAST-Q questionnaire.

CONCLUSIONS

Immediate prepectoral breast reconstruction could represent the ideal reconstruction option after BRRM and should be offered to all women that fulfil the inclusion criteria.

摘要

背景

双侧预防性乳房切除术(BRRM)在过去几年中越来越受欢迎,因为其目的是将高危患者患乳腺癌的几率降至最低。鉴于需要兼顾美观、功能和预防需求,接受该手术的女性必须被视为要求极高的患者。本研究旨在介绍作者在进行BRRM后采用单阶段胸肌前乳房重建术(PPBR)的经验,该重建术使用完全被脱细胞真皮基质(ADM)覆盖的乳房植入物,并报告其适应症、手术技术、功能和美学效果。

方法

从2017年1月至2021年1月,对患有乳腺癌高危风险且接受BRRM和即刻ADM-PPBR的患者进行单中心前瞻性数据收集。根据乳房形状将患者分为两组:A组为中小乳房,B组为大而下垂的乳房。收集肿瘤学和手术结果。通过BREAST-Q问卷评估对重建的满意度和相关生活质量。

结果

共有23名患者符合纳入标准。A组纳入17名患者,B组纳入6名患者。平均随访时间为18.4个月。4个乳房出现轻微并发症:1例血清肿、1例血肿和2例伤口裂开。未观察到包膜挛缩。根据术后BREAST-Q问卷,所有患者对最终结果均满意。

结论

即刻胸肌前乳房重建可能是BRRM术后理想的重建选择,应提供给所有符合纳入标准的女性。

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Epidemiology of Breast Cancer in Women.女性乳腺癌的流行病学。
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