Jia Zhongzhi, Wang Caoye, Paz-Fumagalli Ricardo, Wang Weiping
Department of Interventional Radiology, Second People's Hospital of Changzhou, Changzhou, 213003, China.
The Center of Medical Physics with Nanjing Medical University, Changzhou, 213003, China.
J Interv Med. 2019 Jun 27;2(1):1-4. doi: 10.1016/j.jimed.2019.05.001. eCollection 2019 Feb.
Radiation segmentectomy (RS) is a new approach to Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through radioembolization performed in a segmental fashion, potentially increasing the radiation dose to the tumor while minimizing injury to the liver parenchyma. The aim of this review is to provide a summary of the indications, device choice, dosimetry, procedure, clinical outcomes, and toxicity of RS based on the clinical series currently available.
放射节段切除术(RS)是一种新的钇90放射性栓塞治疗方法,旨在提高不可切除肝脏恶性肿瘤患者放射性栓塞治疗的安全性和有效性。通过这种技术,高剂量(>190 Gy)的辐射通过节段性放射性栓塞传递到肿瘤,有可能增加肿瘤的辐射剂量,同时将对肝实质的损伤降至最低。本综述的目的是根据目前可用的临床系列,总结放射节段切除术的适应症、设备选择、剂量测定、操作过程、临床结果和毒性。