单侧梅尼埃病患者内淋巴积水的磁共振成像：内淋巴间隙的容积比和分布率。
Magnetic resonance imaging of endolymphatic hydrops in patients with unilateral Meniere's disease: volume ratio and distribution rate of the endolymphatic space.
机构信息
Department of Otorhinolaryngology, Inui ENT Clinic, Nara, Japan.
PixSpace. Ltd, Fukuoka, Japan.
出版信息
Acta Otolaryngol. 2021 Dec;141(12):1033-1037. doi: 10.1080/00016489.2021.1968488. Epub 2021 Nov 22.
BACKGROUND
Endolymphatic hydrops (ELH), which is a pathological feature of Meniere's disease (MD), is characterized by an extended endolymphatic space (ELS).
AIMS/OBJECTIVES: We aimed to perform a quantitative volumetric analysis of inner-ear ELH in patients with unilateral MD (uMD).
MATERIAL AND METHODS
This study included 97 patients with definite uMD and 49 control subjects (CS). The ELS/total fluid space (TFS) volume ratio (%) and the distribution rate of the inner-ear components in the ELS (%) were measured using 3D magnetic resonance imaging and compared between patients with uMD and CS.
RESULTS
Compared to CS, patients with uMD had significantly higher mean ELS/TFS volume ratios for inner-ear components. The mean distribution rate of the inner-ear components in the ELS was not significantly different between the two groups.
CONCLUSIONS AND SIGNIFICANCE
In patients with uMD, ELH was noted to be spread throughout the entire inner ear and the endolymph was evenly distributed in the total ELS. These findings should be useful as a standard reference for further research.
背景
内淋巴积水（ELH）是梅尼埃病（MD）的一种病理特征，其特点是延伸的内淋巴间隙（ELS）。
目的
我们旨在对单侧 MD（uMD）患者的内耳 ELH 进行定量容积分析。
材料和方法
本研究纳入了 97 例明确的 uMD 患者和 49 例对照组（CS）。使用 3D 磁共振成像（MRI）测量内耳 ELH 的 ELS/总液空间（TFS）容积比（%）和内耳成分在 ELS 中的分布率（%），并比较 uMD 患者和 CS 之间的差异。
结果
与 CS 相比，uMD 患者的内耳成分 ELS/TFS 容积比显著更高。两组之间内耳成分在 ELS 中的分布率无显著差异。
结论和意义
在 uMD 患者中，ELH 被认为遍及整个内耳，内淋巴在整个 ELS 中均匀分布。这些发现可作为进一步研究的标准参考。
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