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6M50LSG评分系统提高了亚洲人群腹腔镜袖状胃切除术后疑似反应不佳者的足够多余体重减轻比例。

6M50LSG Scoring System Increased the Proportion of Adequate Excess Body Weight Loss for Suspected Poor Responders After Laparoscopic Sleeve Gastrectomy in Asian Population.

作者信息

Chen Jian-Han, Lee Hui-Ming, Chen Chung-Yen, Chen Ying-Chen, Lin Chia-Chen, Su Ching-Yi, Tsai Cheng-Fei, Tu Wan-Ling

机构信息

Bariatric and Metabolism International Surgery Center, E-Da Hospital, Kaohsiung, Taiwan.

Division of General Surgery, E-Da Hospital, Kaohsiung, Taiwan.

出版信息

Obes Surg. 2022 Feb;32(2):398-405. doi: 10.1007/s11695-021-05776-1. Epub 2021 Nov 24.

Abstract

PURPOSE

We aimed to evaluate the efficacy of the predictive tool, 6M50LSG scoring system, to identify suspected poor responders after laparoscopic sleeve gastrectomy (LSG).

METHODS

The 6M50LSG scoring system has been applied since 2019. Suspected poor responders are defined by EBWL at 1 month < 19.5% or EBWL at 3 months < 37.7% based on the 6M50LSG scoring system. Our analysis included 109 suspected poor responders. Based on the date of LSG, the patients were separated into two groups: the 2016-2018 group (before group, BG, with regular care) and the 2019-2020 group (after group, AG, with upgrade medical nutrition therapy).

RESULTS

At the end of the study, the AG group had a significantly higher proportion of adequate weight loss, which was defined as EBWL ≥ 50% at 6 months after LSG, than that in the BG group (18.92% in BG vs. 48.57% in AG, p = 0.003). The AG group demonstrated significantly more 3-months-TWL (BG: 15.22% vs. AG: 17.54%, p < 0.001) and 6-months-TWL (BG: 21.08% vs. AG: 25.65%, p < 0.001). In multivariate analyses and adjustments, the scoring system (AG) resulted in significantly higher chances of adequate weight loss in suspected poor responders (adjusted OR 3.392, 95% CI = 1.345-8.5564, p = 0.010). One year after LSG, suspected poor responders in AG had a significantly higher weight loss than those in BG (BG vs. AG: TWL 27.17% vs. 32.20%, p = 0.014) .

CONCLUSION

This study confirmed that the 6M50LSG scoring system with upgraded medical nutrition therapy increased the proportion of suspected poor responders with adequate weight loss after LSG.

摘要

目的

我们旨在评估预测工具6M50LSG评分系统在识别腹腔镜袖状胃切除术(LSG)后疑似反应不佳者方面的疗效。

方法

6M50LSG评分系统自2019年起开始应用。根据6M50LSG评分系统,1个月时的预期体重减轻(EBWL)<19.5%或3个月时的EBWL<37.7%被定义为疑似反应不佳者。我们的分析纳入了109名疑似反应不佳者。根据LSG的日期,患者被分为两组:2016 - 2018组(之前组,BG,采用常规护理)和2019 - 2020组(之后组,AG,采用升级的医学营养治疗)。

结果

在研究结束时,AG组中达到足够体重减轻(定义为LSG后6个月时EBWL≥50%)的比例显著高于BG组(BG组为18.92%,AG组为48.57%,p = 0.003)。AG组在3个月时的总体重减轻(TWL)显著更多(BG组:15.22% vs. AG组:17.54%,p < 0.001)以及6个月时的TWL(BG组:21.08% vs. AG组:25.65%,p < 0.001)。在多变量分析和调整中,评分系统(AG)使疑似反应不佳者达到足够体重减轻的几率显著更高(调整后的OR为3.392,95%CI = 1.345 - 8.5564,p = 0.010)。LSG后一年,AG组中的疑似反应不佳者体重减轻显著高于BG组(BG组与AG组:TWL分别为27.17% vs. 32.20%,p = 0.014)。

结论

本研究证实,采用升级医学营养治疗的6M50LSG评分系统提高了LSG后疑似反应不佳者达到足够体重减轻的比例。

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