Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Yonsei University College of Medicine, Yonsei University, Seodaemun-gu, South Korea.
J Viral Hepat. 2022 Feb;29(2):156-170. doi: 10.1111/jvh.13636. Epub 2021 Nov 28.
There are limited data to provide better understanding of the knowledge/awareness of general population towards liver health in Asia. We sought to identify the knowledge gaps and attitudes towards liver health and liver diseases as well as evaluate associated individual-level and macro-level factors based on contextual analysis. An online survey assessing knowledge, awareness and attitudes towards liver health and disease was conducted among 7500 respondents across 11 countries/territories in Asia. A liver index was created to measure the respondents' knowledge level and the degree of awareness and attitudes. Multilevel logistic regression was performed to identify individual factors and contextual effects that were associated with liver index. The overall liver index (0-100-point scale) was 62.4 with 6 countries/territories' liver indices greater than this. In the multilevel model, the inclusion of geographical information could explain for 9.6% of the variation. Residing in a country/territory with higher HBV prevalence (80% IOR: 1.20-2.79) or higher HCV death rate (80% IOR: 1.35-3.13) increased the individual probability of obtaining a high overall liver index. Individual factors like age, gender, education, household income, disease history and health screening behaviour were also associated with liver index (all p-values<0.001). The overall liver index was positively associated with the two macro-level factors viz. HBV prevalence and HCV death rate. There is a need to formulate policies especially in regions of lower HBV prevalence and HCV death rate to further improve the knowledge, awareness and attitudes of the general public towards liver diseases.
关于亚洲普通人群对肝脏健康的认识/了解，目前的数据有限。我们旨在根据具体情况分析，找出知识空白，了解人们对肝脏健康和肝脏疾病的态度，并评估相关的个体和宏观因素。我们在亚洲的 11 个国家/地区对 7500 名受访者进行了一项在线调查，评估他们对肝脏健康和疾病的知识、意识和态度。我们创建了一个肝脏指数来衡量受访者的知识水平以及对肝脏健康和疾病的认知和态度程度。我们采用多水平逻辑回归来确定与肝脏指数相关的个体因素和环境因素。总的肝脏指数（0-100 分制）为 62.4，有 6 个国家/地区的肝脏指数高于这一分数。在多水平模型中，纳入地理位置信息可以解释 9.6%的变异。居住在乙型肝炎病毒（HBV）流行率较高（80%IOR：1.20-2.79）或丙型肝炎病毒（HCV）死亡率较高（80%IOR：1.35-3.13）的国家/地区，个人获得高总体肝脏指数的概率增加。年龄、性别、教育程度、家庭收入、疾病史和健康检查行为等个体因素也与肝脏指数相关（均 P 值<0.001）。总体肝脏指数与 HBV 流行率和 HCV 死亡率这两个宏观因素呈正相关。需要制定政策，特别是在 HBV 流行率和 HCV 死亡率较低的地区，以进一步提高普通公众对肝脏疾病的认识、意识和态度。
