Melbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Ciber Fisiopatología Obesidad y Nutrición (CIBERobn), Instituto Salud Carlos III, Barcelona, Spain.
Eur Eat Disord Rev. 2022 Jan;30(1):36-49. doi: 10.1002/erv.2872. Epub 2021 Nov 25.
To assess the clinical significance and distinctiveness of purging disorder (PD) from other eating disorder (ED) diagnoses.
Participants included 3127 women consecutively admitted to an ED treatment centre (246 PD, 465 anorexia nervosa restrictive [AN-R], 327 AN-binge purging [AN-BP], 1436 bulimia nervosa [BN], 360 binge eating disorder [BED], 177 atypical AN and 116 unspecified feeding or eating disorder [UFED]) who were diagnosed according to DSM-5 criteria. Additionally, 822 control participants were recruited from the community. All participants completed measures assessing ED symptoms (EDI-2), general psychopathology (SCL-90-R) and personality (TCI-R).
Patients with PD, when compared to controls, scored significantly higher on the EDI-2 and SCL-90-R, and most TCI-R dimensions. Most of the significant differences between PD and the other ED diagnoses emerged between PD and AN-R, followed by Atypical-AN, UFED, AN-BP and BED, with patients with PD typically reporting higher scores on the EDI-2 and SCL-90-R subscales. Significant differences between PD and BN were also present, but to a lesser extent. The findings for personality varied amongst the different ED diagnoses.
PD is a clinically significant disorder, which seems to be more similar to BN than it is to AN and the other ED subtypes.
评估清除障碍（PD）与其他饮食障碍（ED）诊断的临床意义和独特性。
参与者包括 3127 名连续入住 ED 治疗中心的女性（246 名 PD、465 名神经性厌食症限制型[AN-R]、327 名 AN 暴食清除型[AN-BP]、1436 名神经性贪食症[BN]、360 名暴食障碍[BED]、177 名非典型 AN 和 116 名未指定的进食或饮食障碍[UFED]），他们根据 DSM-5 标准进行了诊断。此外，还从社区招募了 822 名对照参与者。所有参与者都完成了评估 ED 症状（EDI-2）、一般心理病理（SCL-90-R）和人格（TCI-R）的量表。
与对照组相比，PD 患者在 EDI-2 和 SCL-90-R 以及大多数 TCI-R 维度上的得分显著更高。PD 与其他 ED 诊断之间的大多数显著差异出现在 PD 与 AN-R 之间，其次是不典型 AN、UFED、AN-BP 和 BED，PD 患者通常在 EDI-2 和 SCL-90-R 子量表上的得分更高。PD 与 BN 之间也存在显著差异，但程度较轻。人格方面的发现因不同的 ED 诊断而有所不同。
PD 是一种具有临床意义的障碍，它似乎与 BN 更为相似，而不是与 AN 和其他 ED 亚型相似。
