Clinic for Physical Medicine and Rehabilitation, University Clinical Center Tuzla, Medical Faculty University of Tuzla, Bosnia and Herzegovina.
University of Tuzla and University Sarajevo School of Science and Technology.
Acta Med Acad. 2021 Aug;50(2):235-243. doi: 10.5644/ama2006-124.339.
The purpose of this study was to evaluate the efficacy of daily transcutaneous tibial nerve stimulation (TTNS) versus weekly percutaneous tibial nerve stimulation (PTNS) on the quality of life of patients with idiopathic overactive bladder (OAB).
The study was designed as a randomized controlled trial. The diagnosis of OAB was made on the basis of clinical symptoms, and urodynamic tests were performed to check whether uncontrolled contractions of the derusor during bladder filling were responsible for the OAB symptoms. The tests used to assess symptoms and quality of life were Overactive Bladder Questionnaires (OAB-q) SF. The patients were divided into 2 groups of 30 patients each. The first group was treated with TTNS every day for 3 months and the second group with PTNS once a week, also for 3 months.
Stimulation with both TTNS and PTNS led to the reduction of all clinical symptoms of OAB and improved quality of life, with statistical significance (P<0.05) and with no side effects. When comparing these two groups, the improvement was statistically more significant in the group treated with PTNS. When the quality of life scores and symptoms were compared to the type of treatment, it was found that the improved quality of life parameters and the reduced OAB symptoms were more statistically significant in the treatment with PTNS than TTNS therapy (P<0.001).
The results of the study suggest good efficacy of both TTNS and PTNS in the treatment of OAB. Better effects are achieved with weekly PTNS, as it leads to a statistically significant reduction in symptoms as well as an improvement in quality of life, without side effects.
本研究旨在评估经皮胫神经刺激（PTNS）每周一次与经皮胫神经刺激（TTNS）每日一次对特发性逼尿过度活动症（OAB）患者生活质量的疗效。
该研究设计为随机对照试验。OAB 的诊断基于临床症状，进行尿动力学检查以检查膀胱充盈期间逼尿肌的不受控制收缩是否是 OAB 症状的原因。用于评估症状和生活质量的测试是逼尿过度问卷（OAB-q）SF。患者分为两组，每组 30 例。第一组每天接受 TTNS 治疗 3 个月，第二组每周接受 PTNS 治疗 3 个月。
TTNS 和 PTNS 刺激均导致 OAB 的所有临床症状减少，生活质量改善，具有统计学意义（P<0.05），且无副作用。比较这两组时，PTNS 治疗组的改善更具统计学意义。当将生活质量评分和症状与治疗类型进行比较时，发现与 TTNS 治疗相比，PTNS 治疗改善的生活质量参数和减少的 OAB 症状更具有统计学意义（P<0.001）。
研究结果表明 TTNS 和 PTNS 对 OAB 的治疗均有效。每周一次的 PTNS 效果更好，因为它可导致症状明显减少和生活质量明显改善，且无副作用。
