Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Arthroscopy. 2022 Apr;38(4):1288-1298. doi: 10.1016/j.arthro.2021.11.030. Epub 2021 Nov 27.
To identify the individualized method of quantifying lateralization of the tibial tubercle with the best diagnostic effectiveness, as evaluated by measurement repeatability using the intraclass correlation coefficient (ICC), the size of the difference between the case group and the control group, and receiver operating characteristic (ROC) curve analysis.
Patients who had undergone surgery for recurrent patellar dislocation (the case group) and patients who had no history of patellar dislocation (the control group) from January 2014 to December 2019 were included in the study. Six indices that describe lateralization of the tibial tubercle were calculated using either computed tomography (CT) or magnetic resonance imaging (MRI): tibial tubercle lateralization (TTL), tibial tubercle-trochlear groove (TT-TG) ratio, tibial tubercle-posterior cruciate ligament (TT-PCL) ratio, TT-TG index, (TT-TG)/patellar width (PW), and (TT-TG)/trochlear width (TW). Diagnostic effectiveness was evaluated by 1) intra-rater reliability (measurements on two occasions) and inter-rater reliability (measurements by two assessors) using the ICC, 2) the size of the difference between the case group and the control group, and 3) ROC curve analysis, measuring the area under the ROC curve (AUC) and the post hoc power.
100 knees in 88 patients who had undergone surgery for recurrent patellar dislocation and 55 knees in 53 patients who had no history of patellar dislocation were analyzed. The ICC for all the methods were higher than .75. The mean differences between the case group and the control group for TTL, TT-TG ratio, TT-PCL ratio, TT-TG index, (TT-TG)/PW, and (TT-TG)/TW were 2%, 8%, 2%, 12%, 24% and 56%, respectively. The mean differences between the case group and the control group for (TT-TG)/TW was significantly greater than those for the other methods (P < .0001, unpaired t-test). AUC of TTL, TT-TG ratio, TT-PCL ratio, TT-TG index, (TT-TG)/PW, and (TT-TG)/TW were .708, .880, .630, .814, .882, and .905. AUC of (TT-TG)/TW was significantly greater than those of TTL and TT-PCL ratio (P < .0001). The post hoc power for TT-PCL ratio, TT-TG index, (TT-TG)/PW, TT-TG ratio, (TT-TG)/TW, and TTL were 78%, 81%, 88%, 88%, 91%, and 71%, respectively.
Of the six indices evaluated in this study, (TT-TG)/TW showed the greatest mean difference between the two groups, had the greatest diagnostic utility (as measured by AUC values) and had excellent inter-rater and intra-rater reliability (as measured by ICCs). Thus, it may be the best individualized index for diagnosing a lateralized tibial tubercle in patients with recurrent patellar dislocation requiring surgical stabilization compared to patients with no history of patellar dislocation.
Level III, diagnostic study, retrospective cohort study.
通过使用组内相关系数(ICC)评估测量重复性、病例组与对照组之间的差异大小以及接收者操作特征(ROC)曲线分析,确定量化胫骨结节外侧化的最佳个体化方法,其诊断效果最佳。
纳入 2014 年 1 月至 2019 年 12 月期间因复发性髌骨脱位而行手术治疗的患者(病例组)和无髌骨脱位病史的患者(对照组)。使用计算机断层扫描(CT)或磁共振成像(MRI)计算描述胫骨结节外侧化的 6 个指标:胫骨结节外侧化(TTL)、胫骨结节滑车沟(TT-TG)比值、胫骨结节后交叉韧带(TT-PCL)比值、TT-TG 指数、(TT-TG)/髌骨宽度(PW)和(TT-TG)/滑车宽度(TW)。通过 1)评估者内可靠性(两次测量)和评估者间可靠性(由两名评估者进行测量)的 ICC、2)病例组与对照组之间的差异大小以及 3)ROC 曲线分析来评估诊断效果,测量 ROC 曲线下面积(AUC)和事后功效。
分析了 100 例因复发性髌骨脱位而行手术治疗的患者(88 例患者的 100 个膝关节)和 55 例无髌骨脱位病史的患者(53 例患者的 55 个膝关节)。所有方法的 ICC 均高于.75。TTL、TT-TG 比值、TT-PCL 比值、TT-TG 指数、(TT-TG)/PW 和(TT-TG)/TW 病例组与对照组之间的平均差异分别为 2%、8%、2%、12%、24%和 56%。病例组与对照组之间的(TT-TG)/TW 平均差异明显大于其他方法(P <.0001,配对 t 检验)。TTL、TT-TG 比值、TT-PCL 比值、TT-TG 指数、(TT-TG)/PW 和(TT-TG)/TW 的 AUC 分别为.708、.880、.630、.814、.882 和.905。(TT-TG)/TW 的 AUC 明显大于 TTL 和 TT-PCL 比值(P <.0001)。TT-PCL 比值、TT-TG 指数、(TT-TG)/PW、TT-TG 比值、(TT-TG)/TW 和 TTL 的事后功效分别为 78%、81%、88%、88%、91%和 71%。
在本研究评估的 6 个指标中,(TT-TG)/TW 两组之间的平均差异最大,具有最大的诊断效用(以 AUC 值衡量),并且具有良好的评估者间和评估者内可靠性(以 ICC 衡量)。因此,与无髌骨脱位病史的患者相比,它可能是诊断复发性髌骨脱位患者胫骨结节外侧化的最佳个体化指标,这些患者需要手术稳定。
III 级,诊断研究,回顾性队列研究。