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[卵母细胞捐赠妊娠择期剖宫产术中的羊水栓塞与心力衰竭]

[Amniotic fluid embolism and heart failure in elective section in a pregnancy with oocyte donation].

作者信息

Høgh Lisa Maria Bæk, Hamed Nagham Hisham Abdel, Bonefeld Rikke Ekkelund, Andreasen Jo Bønding, Haunstrup Thure Mors, Juhl Karin Hoborg, Morthorst Svenja Nørgaard, Jørgensen Steen Hylgaard

出版信息

Ugeskr Laeger. 2021 Nov 29;183(48).

Abstract

Amniotic fluid embolism (AFE) is a rare obstetric emergency with high maternal morbidity and mortality. Despite ongoing research, the pathogenesis of AFE remains unresolved, and AFE is a diagnostic and therapeutic challenge. We present a case report of suspected AFE and disseminated intravascular coagulation occurring during caesarean delivery in a pregnancy with oocyte donation and intracytoplasmic sperm injection. Awareness of the diagnosis, rapid initiation of treatment and the use of rapid tests of haemostasis in targeted coagulopathy treatment may improve clinical outcome.

摘要

羊水栓塞(AFE)是一种罕见的产科急症,孕产妇发病率和死亡率很高。尽管一直在进行研究,但AFE的发病机制仍未明确,而且AFE在诊断和治疗方面都具有挑战性。我们报告一例在接受卵母细胞捐赠和胞浆内单精子注射的妊娠剖宫产过程中疑似发生AFE及弥散性血管内凝血的病例。提高对该诊断的认识、迅速开始治疗以及在针对性凝血病治疗中使用快速止血检测可能会改善临床结局。

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