Department of Cardiac Intensive Care Unit, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases.
Int Heart J. 2021;62(6):1265-1272. doi: 10.1536/ihj.21-101.
This study assesses the long-term outcomes of patients who suffered from self-expandable transcatheter heart valve (THV) embolized in the aorta in transcatheter aortic valve implantation (TAVI).We retrospectively reviewed the patients with self-expandable THV embolized in the aorta. Follow-up computed tomography was performed to assess the THV migration, struct fractures, and device-related aortic complications.Of the 539 TAVI patients, 11 suffered from self-expandable THV embolized in the aorta. Two patients underwent open-heart surgery to remove the embolized THVs in the ascending aorta. Embolized THVs were repositioned in the aortic arch distal to the left subclavian artery (n = 3) and the thoracic descending aorta (n = 6). Three patients died during a median follow-up time of 40 months. The remaining eight survivors presented with New York Heart Association functional class I or II at the last follow-up. Degeneration of embolized prostheses with thick leaflets and rolled cusp edges was observed in three patients. There was no evidence of valve migration, strut fracture, prosthesis-associated aortic complication, and thrombosis attached on embolized valve for all patients with THVs repositioned in the aorta.Self-expandable THV embolization can be effectively managed in TAVI. Although some embolized valves exhibited leaflet degeneration, the long-term safety of repositioning embolized self-expandable THV in the aorta is assured.
这项研究评估了经导管主动脉瓣置换术(TAVI)中发生自膨式经导管心脏瓣膜(THV)主动脉内栓塞的患者的长期预后。我们回顾性分析了自膨式 THV 主动脉内栓塞的患者。进行了随访计算机断层扫描以评估 THV 迁移、结构骨折和与器械相关的主动脉并发症。在 539 例 TAVI 患者中,有 11 例发生自膨式 THV 主动脉内栓塞。2 例患者接受了开胸手术以取出升主动脉内的栓塞 THV。栓塞的 THV 在左锁骨下动脉远端的主动脉弓(n = 3)和胸降主动脉(n = 6)重新定位。3 例患者在中位随访时间 40 个月时死亡。其余 8 例存活患者在最后一次随访时表现为纽约心脏协会心功能 I 或 II 级。在 3 例患者中观察到栓塞假体的厚瓣叶和卷曲瓣缘的退化。对于所有重新定位在主动脉内的 THV 患者,均未发现瓣膜迁移、支架骨折、假体相关主动脉并发症和血栓附着于栓塞瓣膜。在 TAVI 中可以有效地处理自膨式 THV 栓塞。尽管一些栓塞瓣膜表现出瓣叶退化,但重新定位栓塞自膨式 THV 在主动脉内的长期安全性是有保证的。