Prevalence of drug-resistant microbes in sepsis cases of catheter and fistula based haemodialysis.

BACKGROUND

Chronic stage renal disease is a severe disease of the kidney which affects people globally. According to the global burden of diseases in 2010, this disease has caused more deaths worldwide and due to the high death rate, the ESRD (end-stage renal disease) is now ranked up from 27th to 18th range in the list.

METHODOLOGY

Dialysis samples were collected from the Haripur city and surrounding areas. Samples were inoculated on different selective media for bacterial growth. In addition, different biochemical tests were also performed for identification, where as the resistance genes were identified through a polymerase chain reaction.

RESULT

Out of the total 100 dialysis patient's blood samples, only 17 showed the presence of gram-positive bacteria i.e., while two shown the presence of gram-negative bacteria i.e., and . While in molecular identification two antibiotic resistance genes and A belong to the strain shown their presence.

CONCLUSION

A high infection rate has been observed in fistula-based hemodialysis (17(77.27%)) as compares to catheter-based hemodialysis (5(22.3%) with no significant difference of incidence between the groups (p > 0.05).