Ye Shuang, Hu Jin, Liu Zilong, Liang Man
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Pharmacol. 2021 Nov 11;12:705376. doi: 10.3389/fphar.2021.705376. eCollection 2021.
(Vahl) Endl., known as or Khat is a traditional and regional plant for chewing, smoking and drinking, that has posed a worldwide public health problem due to its recent emerging abused consumption. In the face of the massive use of , we reviewed related publications to analyze the progress and research trends through bibliometric methods. After screening, a total of 514 scientific publications published from 1997 to 2020 were included by systematic retrieval from the Web of Science (WoS) database. According to further scientometric analysis, the annual number of publications output kept rising in most of the years. Ethiopia and the United States of America (USA) have been devoting significant contributions to the field. Though the research emphasis had been the chemical composition and pharmacological and toxicological effects for several years, the hot spots were transferred; the mechanism investigations of have been the focus in recent years, which might be continued in the future. Furthermore, co-operations of multi-disciplinary researchers are needed to minimize abuse harms and maximize the medicinal benefits of to human beings.
（瓦勒）恩德尔，又称巧茶或恰特草，是一种用于咀嚼、吸食和饮用的传统地方植物，由于其最近出现的滥用消费现象，已成为一个全球性的公共卫生问题。面对巧茶的大量使用，我们回顾了相关出版物，通过文献计量学方法分析进展和研究趋势。经过筛选，通过从科学引文索引（WoS）数据库系统检索，共纳入了1997年至2020年发表的514篇科学出版物。根据进一步的科学计量分析，大多数年份的出版物年产量持续上升。埃塞俄比亚和美利坚合众国在该领域做出了重大贡献。尽管多年来研究重点一直是化学成分以及药理和毒理作用，但热点已经转移；近年来巧茶的作用机制研究一直是重点，未来可能会继续。此外，需要多学科研究人员合作，以尽量减少滥用危害，并最大限度地发挥巧茶对人类的药用价值。
