Liu Jiahui, Wang Zhi, Yang Ying, Xiong Yan, Wang Wei, Qiu Jianxing, Zhao Kai, Zheng Bo
Department of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Department of Pathology, Peking University First Hospital, Beijing, China.
Front Cardiovasc Med. 2021 Nov 19;8:758988. doi: 10.3389/fcvm.2021.758988. eCollection 2021.
Primary pericardial mesothelioma is an extremely rare tumor, and early identification and accurate diagnosis may improve its clinical outcome. In this study, we reported a case of a 70-year-old woman who presented with dyspnea. Conventional transthoracic echocardiography showed massive pericardial effusion. Contrast-enhanced ultrasonography revealed a hyper-enhancing mass in the pericardium. Further imaging methods, including cardiac MRI and positron emission tomography/computed tomography, showed invasion of the pericardial mass into the adjacent tissues and distant metastases. Pathologic examination of a puncture biopsy specimen finally confirmed the diagnosis of PPM. Pericardial masses are difficult to detect when a large amount of pericardial effusion is present and the mass is small. The combination of multiple modalities plays a meaningful role in identifying PPM.
原发性心包间皮瘤是一种极其罕见的肿瘤，早期识别和准确诊断可能会改善其临床结局。在本研究中，我们报告了一例70岁出现呼吸困难的女性病例。传统经胸超声心动图显示大量心包积液。对比增强超声检查显示心包内有一个高增强肿块。包括心脏磁共振成像和正电子发射断层扫描/计算机断层扫描在内的进一步成像方法显示心包肿块侵犯了邻近组织并发生远处转移。穿刺活检标本的病理检查最终确诊为原发性心包间皮瘤。当存在大量心包积液且肿块较小时，心包肿块很难被检测到。多种检查方法的联合应用在识别原发性心包间皮瘤方面发挥着重要作用。
