Saemann Michael, Darowski Martin, Hennicke Nina S, Bader Rainer, Sander Manuela, Kluess Daniel
Biomechanics and Implant Technology Research Laboratory, Department of Orthopaedics, Rostock University Medical Center, Doberaner Str. 142, 18057 Rostock, Germany.
Department of Orthopaedics, Rostock University Medical Center, Rostock, Germany.
Clin Biomech (Bristol). 2022 Jan;91:105543. doi: 10.1016/j.clinbiomech.2021.105543. Epub 2021 Nov 29.
The periprosthetic femoral fracture is one of the most severe complications after total hip arthroplasty and is associated with an increased mortality. The underlying causes and the patient- and implant-specific risk factors of periprosthetic femoral fractures remain insufficiently understood. The aim of this study was to gain a more profound understanding of the underlying fracture mechanisms and to provide experimental datasets for validation of computational models.
Six cadaveric femurs were implanted with straight hip stems (Zweymueller design) and loaded until fracture reproducing the clinically relevant load cases stumbling and sideways fall. Displacements and the strain distribution on the surface of the femurs and implants, as well as the fracture load and implant subsidence were measured.
For the load case stumbling the mean fracture load was 6743 N and two different mechanisms leading to fracture could be identified: high subsidence with low femoral bending and small subsidence with high femoral bending. For the load case sideways fall the mean fracture load was 1757 N and both tested femurs fractured due to a rotation of the hip stem around its own axis. The detailed datasets provided by this study can be used in future computational models.
We demonstrated that the underlying fracture mechanisms of periprosthetic femoral fractures can be fundamentally different in the load case stumbling. The seating and exact position of the hip stem in the femur may correlate with implant subsidence and therefore lead to different types of fracture mechanisms resulting in different patient-specific fracture risks.
人工关节周围股骨骨折是全髋关节置换术后最严重的并发症之一,与死亡率增加相关。人工关节周围股骨骨折的潜在原因以及患者和植入物特定的风险因素仍未得到充分了解。本研究的目的是更深入地了解潜在的骨折机制,并为计算模型的验证提供实验数据集。
对六具尸体股骨植入直柄髋关节假体(Zweymueller设计),并加载直至骨折,重现临床相关的负荷情况(绊倒和侧方跌倒)。测量股骨和植入物表面的位移和应变分布,以及骨折负荷和植入物下沉情况。
对于绊倒负荷情况,平均骨折负荷为6743N,可识别出两种导致骨折的不同机制:高下沉伴低股骨弯曲和低下沉伴高股骨弯曲。对于侧方跌倒负荷情况,平均骨折负荷为1757N,两根测试股骨均因髋关节假体绕自身轴线旋转而骨折。本研究提供的详细数据集可用于未来的计算模型。
我们证明,在绊倒负荷情况下,人工关节周围股骨骨折的潜在骨折机制可能存在根本差异。髋关节假体在股骨中的就位情况和精确位置可能与植入物下沉相关,因此会导致不同类型的骨折机制,从而产生不同的患者特异性骨折风险。