Marine Pollution Studies Laboratory, Department of Environmental Toxicology, University of California Davis, 34500 Highway One, Monterey, CA, 93940, USA.
Central Coast Regional Water Quality Control Board, 895 Aerovista Place, Suite 101, San Luis Obispo, CA, 93401-7906, USA.
Bull Environ Contam Toxicol. 2022 May;108(5):884-889. doi: 10.1007/s00128-021-03416-z. Epub 2021 Dec 7.
Organism tolerance thresholds for emerging contaminants are vital to the development of water quality criteria. Acute (96-h) and chronic (10-day) effects thresholds for neonicotinoid pesticides clothianidin and thiamethoxam, and the carbamate pesticide methomyl were developed for the midge Chironomus dilutus to support criteria development using the UC Davis Method. Median lethal concentrations (LC50s) were calculated for acute and chronic exposures, and the 25% inhibition concentrations (IC25) were calculated for the chronic exposures based on confirmed chemical concentrations. Clothianidin effect concentrations were 4.89 µg/L, 2.11 µg/L and 1.15 µg/L for 96-h LC50, 10-day LC50 and 10-day IC25, respectively. Similarly, thiamethoxam concentrations were 56.4 µg/L, 32.3 µg/L and 19.6 µg/L, and methomyl concentrations were 244 µg/L, 266 µg/L and 92.1 µg/L. Neonicotinoid effect concentrations compared favorably to previously published 96-h and 14-day LC50 concentrations, and methomyl effect concentrations were within the acute survival range reported for Chironomus species and other organisms.
对于新兴污染物,生物体的耐受阈值对于水质标准的制定至关重要。为了支持使用加州大学戴维斯分校方法制定标准,我们针对摇蚊 Chironomus dilutus 开发了新烟碱类杀虫剂噻虫嗪和噻虫胺,以及氨基甲酸酯类杀虫剂涕灭威的急性(96 小时)和慢性(10 天)效应阈值。计算了急性和慢性暴露的致死中浓度(LC50),并根据确认的化学浓度计算了慢性暴露的 25%抑制浓度(IC25)。噻虫嗪的效应浓度分别为 96 小时 LC50、10 天 LC50 和 10 天 IC25 的 4.89µg/L、2.11µg/L 和 1.15µg/L。同样,噻虫胺的浓度分别为 56.4µg/L、32.3µg/L 和 19.6µg/L,涕灭威的浓度分别为 244µg/L、266µg/L 和 92.1µg/L。新烟碱类的效应浓度与先前公布的 96 小时和 14 天 LC50 浓度相比表现良好,而涕灭威的效应浓度在报道的摇蚊属和其他生物的急性生存范围内。