NK细胞活性受损可能会降低贝那利珠单抗的抗嗜酸性粒细胞疗效。 - Suppr

Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity.

作者信息

Poznanski Sophie M, Portillo Ana, Mukherjee Manali, Bhalla Anurag, Son Kiho, Ashkar Ali A, Khalidi Nader, Nair Parameswaran

机构信息

Division of Clinical Immunology and Allergy, McMaster University and St Joseph's Healthcare, Hamilton, ON, Canada.

Division of Respirology, McMaster University and St Joseph's Healthcare, Hamilton, ON, Canada.

出版信息

Eur Respir J. 2022 Apr 7;59(4). doi: 10.1183/13993003.02210-2021. Print 2022 Apr.

DOI:10.1183/13993003.02210-2021

PMID:34887323

Abstract

摘要

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Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity.

Eur Respir J. 2022 Apr 7;59(4). doi: 10.1183/13993003.02210-2021. Print 2022 Apr.

Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity.

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Expert Opin Biol Ther. 2017 Jul;17(7):895-900. doi: 10.1080/14712598.2017.1319471. Epub 2017 Apr 19.

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Curr Med Res Opin. 2017 Sep;33(9):1605-1613. doi: 10.1080/03007995.2017.1347091. Epub 2017 Jul 19.

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Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity.

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Benralizumab's anti-eosinophil efficacy may be decreased by impaired NK cell activity.

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