Department of Intensive Care Unit, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
J Healthc Eng. 2021 Nov 30;2021:5327682. doi: 10.1155/2021/5327682. eCollection 2021.
To study lung function impairment by meta-analysis to increase the risk of postoperative respiratory failure in patients with esophageal carcinoma.
We searched PubMed, ScienceDirect, and CNKI and other databases, and the search time was set to the time the database was established. We screened the relevant literature to study the relationship between lung function damage and postoperative respiratory failure in patients with esophageal cancer, determined to include the literature and extracted relevant data, and then, applied NOS. The scale evaluates the quality of the literature, and the ReviewManager software was used to perform meta-analysis on the extracted data.
Finally, 9 related articles and 2822 research subjects were included, and the average score of literature quality was 5.78 points, the heterogeneity of the literature was large ( = 84%), the random effects model was used for analysis, and the correlation between the two showed SMD = 0.09, 95%CI[-0.09, 0.31], = 1.10, = 0.27, which is consistent with the results of the subgroup analysis.
The results of the study show that lung function impairment has a positive relationship with postoperative respiratory failure in patients with esophageal cancer. Pulmonary function impairment in cases with different case characteristics can also aggravate the severity of respiratory failure.
通过荟萃分析研究肺功能损害增加食管癌患者术后呼吸衰竭的风险。
我们检索了 PubMed、ScienceDirect 和中国知网等数据库,并将搜索时间设置为数据库建立的时间。我们筛选了相关文献,以研究肺功能损害与食管癌患者术后呼吸衰竭之间的关系,确定纳入文献并提取相关数据,然后应用 NOS 量表评估文献质量,使用 ReviewManager 软件对提取的数据进行荟萃分析。
最终纳入 9 篇相关文献和 2822 例研究对象,文献质量平均评分为 5.78 分,文献异质性较大( = 84%),采用随机效应模型进行分析,相关性分析结果显示 SMD = 0.09,95%CI[-0.09, 0.31], = 1.10, = 0.27,与亚组分析结果一致。
研究结果表明,肺功能损害与食管癌患者术后呼吸衰竭呈正相关。不同病例特征的肺功能损害也可加重呼吸衰竭的严重程度。