Tanabe J, Nakazato H, Tanabe H, Hanasaki H, Kawasaki K, Yonemura D
Doc Ophthalmol. 1986 Jul 15;63(2):165-71. doi: 10.1007/BF00157127.
The spectral response curve (amplitude versus wavelength) of the R2 of the early receptor potential (ERP) was studied in normal, protan, and deutan subjects. The R2 amplitude peaked at 520 nm in most normal subjects. The R2 at long wavelengths was smaller than normal in protans and larger than normal in deutans when the maximum amplitudes were normalized to 100% at the peak. The ratio of the R2 amplitude at 460 nm to that at 600 nm clearly differed between protans and deutans. The ERP and the rapid off-response, which is mainly due to the cessation of the late receptor potential, were recorded in the same subjects. The ratio of the sensitivity of the rapid off-response at 500 nm to that at 600 nm was correlated with the ratio of the R2 amplitude at 460 nm to that at 600 nm (correlation coefficient, 0.823, p less than 0.001). This study, in conjunction with our previous study, indicates that the abnormality is in the outer segments of the cones in protans and deutans.
我们研究了正常受试者、红色盲受试者和绿色盲受试者早期感受器电位（ERP）中R2的光谱响应曲线（振幅与波长的关系）。在大多数正常受试者中，R2振幅在520nm处达到峰值。当将最大振幅在峰值处归一化为100%时，红色盲受试者长波长处的R2小于正常，而绿色盲受试者长波长处的R2大于正常。红色盲受试者和绿色盲受试者在460nm处的R2振幅与600nm处的R2振幅之比明显不同。在同一受试者中记录了ERP和主要由晚期感受器电位终止引起的快速消退反应。500nm处快速消退反应的敏感性与600nm处快速消退反应的敏感性之比，与460nm处的R2振幅与600nm处的R2振幅之比相关（相关系数为0.823，p<0.001）。这项研究与我们之前的研究共同表明，红色盲和绿色盲受试者的视锥细胞外段存在异常。
