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颈椎前路椎间盘切除融合术中保留与去除椎体终板治疗脊髓型颈椎病的临床疗效比较

Comparison of clinical efficacy between retention and removal of the vertebral bony endplate in anterior cervical discectomy and fusion for the treatment of cervical spondylotic myelopathy.

作者信息

Li Mi, Zhang Tao, Zhang Hanjun, Zhang Rui, Li Huazhe, Gou Xusheng

机构信息

Department of Orthopedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.

Department of Orthopedic Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.

出版信息

J Orthop Sci. 2023 Jan;28(1):123-130. doi: 10.1016/j.jos.2021.10.020. Epub 2021 Dec 9.

Abstract

BACKGROUND

Anterior cervical discectomy and fusion (ACDF) have a history of more than 60 years to treat cervical spondylotic myelopathy. This study is based on the original classic surgical procedure to remove the bony endplate to expand the range of vertical decompression to analyze and compare the clinical efficacy of two different ACDF in treating cervical spondylotic myelopathy.

METHODS

The inpatients in hospital were randomly divided into two groups A and B. Patients in Group A received ACDF surgery with bony endplates preserved, and patients in group B received ACDF surgery with bony endplates removed. All patients were followed-up for three years, and then compared the clinical efficacy from the following aspects, blood loss statistics during and after the operation, Japanese Orthopedic Association's scoring (JOA) standard for cervical spondylotic myelopathy, Cervical curvature index, cervical flexion and extension range, intervertebral bone graft fusion time and fusion rate.

RESULTS

  1. The operative time and intraoperative (postoperative) blood loss in group A were significantly better than that in group B, with statistical significance (P < 0.05)0.2. There was no significant difference in postoperative neurological function recovery, cervical curvature index, cervical flexion and extension activity, and Intervertebral fusion time between two groups (P > 0.05), while group A was superior to group B in terms of bone graft fusion rate (P < 0.05). 3. Four patients (6.7%) in group B suffered from dyspnea due to neck hematoma caused by drainage tube blockage, but all of them were cured immediately and no death occurred.

CONCLUSIONS

During the 3-year follow-up period after the operation, six patients in group B have subsidence and loosening of the internal fixator due to bone subsidence around the implant. Although immediate surgical treatment is not required, renovation surgery is inevitable in the long term.

摘要

背景

颈椎前路椎间盘切除融合术(ACDF)治疗脊髓型颈椎病已有60多年的历史。本研究基于经典的原始手术方法,去除骨终板以扩大垂直减压范围,分析比较两种不同的ACDF治疗脊髓型颈椎病的临床疗效。

方法

将住院患者随机分为A、B两组。A组患者接受保留骨终板的ACDF手术,B组患者接受去除骨终板的ACDF手术。对所有患者进行三年随访,然后从以下方面比较临床疗效,手术中和手术后的失血量统计、日本骨科协会脊髓型颈椎病评分(JOA)标准、颈椎曲度指数、颈椎屈伸范围、椎间植骨融合时间和融合率。

结果

  1. A组的手术时间和术中(术后)失血量明显优于B组,差异有统计学意义(P<0.05)。2. 两组术后神经功能恢复、颈椎曲度指数、颈椎屈伸活动度和椎间融合时间比较,差异无统计学意义(P>0.05),而A组在植骨融合率方面优于B组(P<0.05)。3. B组有4例患者(6.7%)因引流管堵塞导致颈部血肿出现呼吸困难,但均立即治愈,无死亡病例。

结论

术后三年随访期间,B组有6例患者因植入物周围骨质塌陷导致内固定器下沉和松动。虽然不需要立即进行手术治疗,但从长远来看翻修手术是不可避免的。

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