Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Upper Mayuanlin Road 238, Changsha, Hunan, China; Division of Prevention and Community Research, Department of Psychiatry, Yale School of Medicine, 389 Whitney Avenue, New Haven, CT, USA.
Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Upper Mayuanlin Road 238, Changsha, Hunan, China.
Schizophr Res. 2022 Jan;239:168-175. doi: 10.1016/j.schres.2021.11.043. Epub 2021 Dec 10.
We examine the relationship between two perspectives on recovery from schizophrenia: clinical recovery and personal recovery. Clinical recovery emphasizes an individual's psychiatric symptoms and functioning, whereas personal recovery emphasizes adaptation to one's illness that includes taking responsibility for one's recovery, establishing an identity apart from the illness, and finding meaning, purpose, and hope in life.
Using serial mediation analysis, we examine the relationship between clinical and personal recovery in the context of two potential mediators, disability and quality of life. Study participants were 356 people with a diagnosis of schizophrenia and living with family in Changsha City of Hunan Province, China.
Although clinical recovery was modestly associated with personal recovery (r = 0.27, p < 0.001), subsequent serial mediation analysis showed that clinical recovery is not directly related to personal recovery when accounting for disability and quality of life. Clinical recovery was a significant predictor of disability, which predicted quality of life and personal recovery. Among the three mediation paths, quality of life accounted for most of the mediation effect (54%), followed by disability (24%), and disability and quality of life serially (22%). We discuss the implications of these findings for theory development, intervention, and future research.
我们探讨了精神分裂症康复的两种观点之间的关系：临床康复和个人康复。临床康复强调个体的精神症状和功能，而个人康复则强调对疾病的适应，包括对自己的康复负责，在疾病之外建立身份认同，并在生活中找到意义、目的和希望。
采用序列中介分析，我们在残疾和生活质量两个潜在中介的背景下，检验了临床和个人康复之间的关系。研究参与者是 356 名在中国湖南省长沙市与家人一起生活的精神分裂症患者。
尽管临床康复与个人康复有适度的关联（r=0.27，p<0.001），但随后的序列中介分析表明，在考虑残疾和生活质量时，临床康复与个人康复之间没有直接关系。临床康复是残疾的一个显著预测因素，而残疾又预测了生活质量和个人康复。在三个中介路径中，生活质量占中介效应的大部分（54%），其次是残疾（24%），残疾和生活质量依次占（22%）。我们讨论了这些发现对理论发展、干预和未来研究的意义。
