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产后子痫前期女性的胆囊壁增厚:一例报告

Gallbladder wall thickening in a woman with postpartum preeclampsia: A case report.

作者信息

Murata Tsuyoshi, Yoshimoto Yuki, Shibano Yoshiaki, Nakamura Soichi, Yamauchi Ryuji

机构信息

Department of Obstetrics and Gynecology, Shirakawa Kosei General Hospital, Fukushima 961-0005, Japan.

出版信息

Case Rep Womens Health. 2021 Nov 15;33:e00370. doi: 10.1016/j.crwh.2021.e00370. eCollection 2022 Jan.

Abstract

BACKGROUND

Preeclampsia (PE) is hallmarked by dysfunction of various organs; therefore, its diagnosis can be challenging, especially when patients present with right upper abdominal pain. Herein, we present a case of postpartum gallbladder wall thickening (GBWT) that led to a diagnosis of PE, rather than hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome or gallbladder and biliary disease.

CASE PRESENTATION

A 31-year-old postpartum woman presented with a fever, hypertension, headache, and right upper abdominal pain. HELLP syndrome and intracranial hemorrhage were initially suspected, due to the combination of symptoms and elevated levels of aspartate transaminase, alanine transaminase, and lactate dehydrogenase. However, hemolysis and thrombocytopenia were absent, and a computed tomography (CT) scan of the head did not indicate the presence of intracranial hemorrhage. Further, transabdominal ultrasound and CT revealed GBWT (edematous gallbladder); CT also revealed an enlarged heart, lung edema, pleural effusion, and ascites. Thus, PE, rather than HELLP syndrome or gallbladder or biliary disease, was diagnosed based on gestational hypertension and proteinuria, new-onset headache, liver dysfunction, and edema in several organs, including the lung. Nicardipine treatment quickly improved hypertension and headache, and, over time, the patient's urination increased, and edema subsided throughout the body. Furthermore, laboratory results improved, and the patient was discharged on postpartum day 11.

CONCLUSION

Postpartum gallbladder wall thickening can be a diagnostic sign of PE.

摘要

背景

子痫前期(PE)的特征是多个器官功能障碍;因此,其诊断可能具有挑战性,尤其是当患者出现右上腹疼痛时。在此,我们报告一例产后胆囊壁增厚(GBWT)导致诊断为PE的病例,而非溶血、肝酶升高和血小板减少综合征(HELLP)或胆囊及胆道疾病。

病例介绍

一名31岁的产后女性出现发热、高血压、头痛和右上腹疼痛。由于症状以及天冬氨酸转氨酶、丙氨酸转氨酶和乳酸脱氢酶水平升高,最初怀疑为HELLP综合征和颅内出血。然而,不存在溶血和血小板减少,头部计算机断层扫描(CT)未显示颅内出血。此外,经腹超声和CT显示GBWT(胆囊水肿);CT还显示心脏扩大、肺水肿、胸腔积液和腹水。因此,基于妊娠期高血压和蛋白尿、新发头痛、肝功能障碍以及包括肺部在内的多个器官出现水肿,诊断为PE,而非HELLP综合征或胆囊或胆道疾病。尼卡地平治疗迅速改善了高血压和头痛,随着时间推移,患者尿量增加,全身水肿消退。此外,实验室检查结果改善,患者于产后第11天出院。

结论

产后胆囊壁增厚可能是PE的一个诊断体征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6efa/8637342/b7d741444032/gr1.jpg

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