F-FDG PET/CT 检测到不常见的孤立性鼻腔髓外浆细胞瘤。

Uncommon solitary nasal extramedullary plasmacytoma detected by F-FDG PET/CT.

机构信息

Nuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, Ferrara, Italy. Via Aldo Moro 8, CAP 44124, Ferrara, Italy.

出版信息

Hell J Nucl Med. 2021 Sep-Dec;24(3):265-266. doi: 10.1967/s002449912409. Epub 2021 Dec 17.

DOI:10.1967/s002449912409

PMID:34901966

Abstract

Extramedullary plasmacytoma (EMP) is an uncommon neoplastic proliferation of monoclonal plasma cells. Despite having a better prognosis and lower conversion rate to multiple myeloma in comparison to solitary bone plasmacytoma, EMP diagnosis can be challenging. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) certainly has an established role in EMP diagnostic workup. Herein, we describe a rare case of nasal cavity EMP, highlighting F-FDG PET/CT potential in the detection of EMP occurring in atypical sites and providing a useful comparison in the differential diagnosis with other F-FDG avid nasal pathologies.

摘要

髓外浆细胞瘤（EMP）是单克隆浆细胞的一种罕见肿瘤性增生。尽管与孤立性骨浆细胞瘤相比，EMP 的预后更好，多发性骨髓瘤转化率更低，但 EMP 的诊断具有一定挑战性。氟-18-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）在 EMP 诊断中具有明确的作用。在此，我们描述了一例鼻腔 EMP 的罕见病例，强调了 F-FDG PET/CT 在检测非典型部位发生的 EMP 中的作用，并在与其他 F-FDG 摄取的鼻腔病变的鉴别诊断中提供了有用的比较。