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放松运动疗法对重度动脉高血压患者的治疗有效吗?

Is relaxation exercise therapy effective in the management of patients with severe arterial hypertension?

作者信息

Lebedeva Olga D, Achilov Abduahat A, Mavlyanova Zilola F, Baranov Alexey V, Achilova Shachnosa A, Sanina Natalia P, Fesyun Anatoly D, Rachin Andrey P, Yakovlev Maxim Yu, Terentev Kirill V, Reverchuk Igor V, Velilyaeva Alie S, Maccarone Maria Chiara, Masiero Stefano

机构信息

Federal State Budgetary Institution "National medical research center for rehabilitation and balneology", Ministry of Health of Russia, Moscow.

Federal State Budgetary Institution "Skobelkin State Scientific Center of Laser Medicine Federal Medical and Biological Agency of Russia", Moscow.

出版信息

Eur J Transl Myol. 2021 Dec 15;31(4):10327. doi: 10.4081/ejtm.2021.10327.

Abstract

Arterial hypertension (AH) is a burning problem in the world. Antihypertensive pharmacological therapy combined by physical exercises is well-studied in patients with mild and moderate AH. However, studies that have investigated relaxation in patients with severe AH in addition to drug therapy are lacking. Optimization of a comprehensive treatment for patients with severe AH, by using a multicomponent rational antihypertensive pharmacotherapy (PT) with subsequent application of relaxation exercise therapy (RET). The study involved 32 male patients with severe AH. Initially, clinical-instrumental and laboratory examination, blood pressure registration and daily arterial blood pressure monitoring were carried out. Suitable PT was selected for all the patients. 3 months after starting PT the patients were divided in 2 groups. The patients of the 1st group were prescribed RET in addition to PT. The 2nd group of patients continued receiving PT alone. 3 months later, average daily blood pressure (ADBP)-syst and ADBP-diast were compared in both groups. Three months after PT both groups demonstrated a significant decrease in ADBP-syst and ADBP diast, but these indicators remained higher than normal and did not reach the target level. Three months after the inclusion of RET in the comprehensive treatment, the 1st group demonstrated a significant decrease in ADBP (systolic and diastolic), not only in comparison with the initial data, but also with the data observed three months after PT. After 6 months, ADBP-syst and ADBP-diast in the 1st group were significantly lower compared with those of patients in the 2nd group. The inclusion of RET in addition to a multicomponent antihypertensive PT is a promising treatment option for severe AH.

摘要

动脉高血压(AH)是全球一个亟待解决的问题。在轻度和中度AH患者中,抗高血压药物治疗联合体育锻炼已得到充分研究。然而,缺乏针对重度AH患者在药物治疗基础上进行放松治疗的研究。通过采用多组分合理抗高血压药物治疗(PT)并随后应用放松运动疗法(RET),优化重度AH患者的综合治疗方案。该研究纳入了32名重度AH男性患者。最初,进行了临床仪器和实验室检查、血压记录以及每日动脉血压监测。为所有患者选择了合适的PT。开始PT治疗3个月后,将患者分为两组。第一组患者除PT外还接受RET治疗。第二组患者继续仅接受PT治疗。3个月后,比较两组患者的平均每日收缩压(ADBP-syst)和平均每日舒张压(ADBP-diast)。PT治疗3个月后,两组患者的ADBP-syst和ADBP-diast均显著下降,但这些指标仍高于正常水平,未达到目标值。在综合治疗中加入RET治疗3个月后,第一组患者的ADBP(收缩压和舒张压)不仅与初始数据相比显著下降,而且与PT治疗3个月后的观察数据相比也显著下降。6个月后,第一组患者的ADBP-syst和ADBP-diast显著低于第二组患者。在多组分抗高血压PT基础上加入RET是重度AH患者一种有前景的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637e/8758959/d851c27b3295/ejtm-31-4-10327-g001.jpg

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