分析血清 L-精氨酸和 25-羟维生素 D 水平作为严重先兆子痫母亲生存的预测指标。

Analysis of serum levels L-arginine and 25-hydroxyvitamin D as a predictor of survival of severe preeclampsia mothers.

机构信息

Department of Midwifery, Graduate School, Hasanuddin University, Makassar, Indonesia.

出版信息

Gac Sanit. 2021;35 Suppl 2:S224-S226. doi: 10.1016/j.gaceta.2021.10.026.

DOI:10.1016/j.gaceta.2021.10.026

PMID:34929817

Abstract

OBJECTIVE

This study aimed to analyze serum levels of L-arginine and 25-hydroxyvitamin D as predictors of survival in severely preeclamptic women.

METHODS

This study is a retrospective descriptive study using medical record data from June to August 2019 and has received a recommendation for ethical approval with the protocol number UH20070290. The study was conducted in 4 hospitals in Makassar: Dr. General Hospital. Wahidin Sudirohusodo, Hasanuddin University Teaching Hospital, Siti Fatimah Regional Mother and Child Health Hospital, and Sitti Khadijah 1 Mother and Child Hospital. The samples of this study were mothers who gave birth with a diagnosis of normal pregnant women, severe preeclampsia, and severe preeclampsia with complications.

RESULTS

Serum l-arginine level did not affect the survival of severe preeclamptic mothers. It was shown at p-value 0.799>0.05. Meanwhile, serum levels of 25-hydroxyvitamin D affect the predictors of maternal preeclampsia where the p-value is 0.024<0.05. In comparing serum levels of L-arginine and 25-hydroxyvitamin D, there was no significant difference in groups of normal pregnant women, severe preeclampsia, and severe preeclampsia with complications.

CONCLUSION

Serum level of 25-hydroxyvitamin affects the survival of severe preeclamptic mothers.

摘要

目的

本研究旨在分析血清 L-精氨酸和 25-羟维生素 D 水平作为严重子痫前期妇女生存预测因子。

方法

本研究为回顾性描述性研究，使用 2019 年 6 月至 8 月的病历数据，并获得了伦理批准建议，编号为 UH20070290。研究在 4 家位于望加锡的医院进行：Wahidin Sudirohusodo 将军医院、哈桑努丁大学教学医院、Siti Fatimah 地区母婴保健医院和 Sitti Khadijah 1 母婴保健医院。本研究的样本为被诊断为正常孕妇、严重子痫前期和严重子痫前期合并并发症的产妇。

结果

血清 L-精氨酸水平并不影响严重子痫前期产妇的生存率。p 值为 0.799>0.05。同时，血清 25-羟维生素 D 水平影响子痫前期产妇的预测因子，p 值为 0.024<0.05。在比较正常孕妇、严重子痫前期和严重子痫前期合并并发症三组之间的血清 L-精氨酸和 25-羟维生素 D 水平时，差异无统计学意义。