Gurkan Selami, Gur Ozcan, Sahin Ayhan, Donbaloglu Mehmet
Department of Cardiovascular Surgery, 472605Namik Kemal Universitesi Tip Fakultesi, Tekirdag, Turkey.
Department of Anesthesiology, 472605Namik Kemal Universitesi Tip Fakultesi, Tekirdag, Turkey.
Vascular. 2023 Apr;31(2):211-218. doi: 10.1177/17085381211063316. Epub 2021 Dec 21.
Obesity is a common and growing health problem in vascular surgery patients, as it is in all patient groups. Evidence regarding body mass index (BMI) on endovascular aneurysm repair (EVAR) outcomes is not clear in the literature. We aimed to determine the impact of obesity on perioperative and midterm outcomes of elective EVAR between obese and non-obese patients.
Under a retrospective study design, a total of 120 patients (109 males, 11 females, mean age: 74.45 ± 8.59 (53-92 years)) undergoing elective EVAR between June 2012 and May 2020 were reviewed. Patients were stratified into two groups: obese (defined as a body mass index (BMI) ≥ 30 kg/m) and non-obese (mean BMI < 30 kg/m (32.25 ± 1.07 kg/m vs 25.85 ± 2.69 kg/m)).
Of the 120 patients included in the study, 81 (67.5%) were defined as "nonobese," while 39 (32.5%) were obese. The mean BMI of the study group was 27.93 ± 3.78 kg/m. In obese patients, the procedure time, fluoroscopy time, and dose area product (DAP) values were longer than those of non-obese patients: 89.74 ± 20.54 vs 79.69 ± 28.77 min ( = 0.035), 33.23 ± 10.14 vs 38.17 ± 8.61 min ( = 0.01) and 133.69 ± 58.17 vs 232.56 ± 51.87 Gy.cm ( < 0.001). Although there was no difference in sac shrinkage at 12-month follow-up, there was a significant decrease at 6-month follow-up in both groups ( = 0.017). Endoleak occurred in 17.9% ( = 7) of the obese group versus 11.1% ( = 9) of the non-obese group ( = 0.302). Iliac branch occlusion developed in four patients, 3 (3.7%) in the non-obese group and 1 (2.6%) in the obese group ( = 0.608). The all-cause mortality rate was slightly higher in the obese group; however, it did not differ between the groups ( = 0.463).
In addition to the longer procedure times, fluoroscopy times, and DAP values in obese patients, regardless of obesity, significant sac shrinkage in the first 6 months of follow-up was observed in both groups. No difference was documented with regards to mortality or morbidity following EVAR.
肥胖是血管外科患者中常见且日益严重的健康问题,所有患者群体皆是如此。关于体重指数(BMI)对血管内动脉瘤修复(EVAR)结果的影响,文献中的证据并不明确。我们旨在确定肥胖对肥胖患者和非肥胖患者择期EVAR围手术期及中期结果的影响。
在回顾性研究设计下,对2012年6月至2020年5月期间接受择期EVAR的120例患者(109例男性,11例女性,平均年龄:74.45±8.59岁(53 - 92岁))进行了回顾。患者被分为两组:肥胖组(定义为体重指数(BMI)≥30 kg/m²)和非肥胖组(平均BMI < 30 kg/m²(32.25±1.07 kg/m² vs 25.85±2.69 kg/m²))。
在纳入研究的120例患者中,81例(67.5%)被定义为“非肥胖”,而39例(32.5%)为肥胖。研究组的平均BMI为27.93±3.78 kg/m²。肥胖患者的手术时间、透视时间和剂量面积乘积(DAP)值均长于非肥胖患者:89.74±20.54 vs 79.69±28.77分钟(P = 0.035),33.23±10.14 vs 38.17±8.61分钟(P = 0.01)以及133.69±58.17 vs 232.56±51.87 Gy.cm²(P < 0.001)。尽管在12个月随访时瘤囊缩小情况无差异,但两组在6个月随访时均有显著下降(P = 0.017)。肥胖组内漏发生率为17.9%(n = 7),非肥胖组为11.1%(n = 9)(P = 0.302)。4例患者发生髂支闭塞,非肥胖组3例(3.7%),肥胖组1例(2.6%)(P = 0.608)。肥胖组全因死亡率略高;然而,两组之间无差异(P = 0.463)。
除了肥胖患者手术时间、透视时间和DAP值较长外,无论肥胖与否,两组在随访的前6个月均观察到瘤囊显著缩小。EVAR术后死亡率或发病率无差异。