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人类胎儿膝状神经节的发育

Development of the Geniculate Ganglion in Human Fetuses.

作者信息

Dagtekin Oykut, Beger Orhan, Taghipour Pourya, Dagtekin Ahmet, Ors Alev Bobus, Vayisoglu Yusuf, Talas Derya Umit

机构信息

Mersin City Hospital, Department of Histology and Embryology, Mersin, Turkey.

出版信息

Turk Neurosurg. 2022;32(3):406-411. doi: 10.5137/1019-5149.JTN.35393-21.2.

Abstract

AIM

To present the quantitative development of the geniculate ganglion (GG) in foetal cadavers.

MATERIAL AND METHODS

This study focused on 60 temporal bones of 30 (15 female and 15 male) foetuses aged 18?30 weeks of gestation (mean age, 22.83 ± 3.49 weeks) to measure the length, width and area of the GG.

RESULTS

According to gestational weeks and months, the ganglion length (1.21 ± 0.41 mm), width (1.03 ± 0.28 mm) and area (1.24 ± 0.61 mm < sup > 2 < /sup > ) did not change. In terms of sexes or sides, ganglion dimensions were not significantly different. Positive correlation was found between the length and width (p=0.033, r=0.276), between the length and area (p < 0.001, r=0.762) and between the width and area (p < 0.001, r=0.622). Linear functions were calculated for the ganglion area (y=0.355 + 0.039 × weeks), length (y=0.636 + 0.025 × weeks) and width (y=0.634 + 0.017 × weeks).

CONCLUSION

The ganglion size did not change in foetal cadavers aged 18?30 weeks of gestation. This finding may be important for anatomists and embryologists in performing morphometric studies and understanding the development of the GG and for neurootologists and neurosurgeons in achieving greater success in skull base surgeries.

摘要

目的

呈现胎儿尸体中膝状神经节(GG)的定量发育情况。

材料与方法

本研究聚焦于30例(15例女性和15例男性)妊娠18至30周(平均年龄22.83±3.49周)胎儿的60块颞骨,以测量GG的长度、宽度和面积。

结果

根据孕周和月份,神经节长度(1.21±0.41毫米)、宽度(1.03±0.28毫米)和面积(1.24±0.61平方毫米)未发生变化。在性别或左右侧方面,神经节尺寸无显著差异。发现长度与宽度之间存在正相关(p = 0.033,r = 0.276),长度与面积之间存在正相关(p < 0.001,r = 0.762),宽度与面积之间存在正相关(p < 0.001,r = 0.622)。计算了神经节面积(y = 0.355 + 0.039×孕周)、长度(y = 0.636 + 0.025×孕周)和宽度(y = 0.634 + 0.017×孕周)的线性函数。

结论

妊娠18至30周胎儿尸体中的神经节大小未发生变化。这一发现对于解剖学家和胚胎学家进行形态计量学研究以及理解GG的发育可能具有重要意义,对于耳神经科医生和神经外科医生在颅底手术中取得更大成功也可能具有重要意义。

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