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肺部受累、临床和实验室参数对老年 2019 冠状病毒病患者结局的影响。

The effects of lung involvement, clinical and laboratory parameters on outcome in elderly patients with coronavirus disease 2019.

机构信息

Department of Allergy and Immunology, Ataturk Training and Research Hospital, Izmir Katip Çelebi University.

Department of Infectious Diseases and Clinical Microbiology, Izmir Bozyaka Training and Research Hospital, University of Health Sciences, Izmir, Turkey.

出版信息

Blood Coagul Fibrinolysis. 2022 Apr 1;33(3):162-166. doi: 10.1097/MBC.0000000000001119. Epub 2021 Dec 22.

Abstract

We aimed to investigate the association of lung involvement and biochemical parameters with patients' demographic characteristics, and how this association effects the disease course and mortality in elderly patients diagnosed with coronavirus disease 2019 (COVID-19). Age, degree of pulmonary involvement, comorbidities, and biochemical parameters of 211 patients who were 60 years or older, diagnosed with COVID-19, and had lung involvement were analyzed. The effects of these parameters on ICU admission and mortality were investigated. Advanced age, severity of lung involvement, elevated D-dimer, ferritin, and fibrinogen levels, and a previous history ofchronic obstructive pulmonary disease (COPD)were significant for predicting ICU admission and mortality. Along with advanced age, both the severity of lung involvement and a history of COPD had major impact on mortality in the course of COVID-19.

摘要

目的

探讨肺部受累及生化参数与患者人口统计学特征的相关性,以及这种相关性如何影响老年 2019 冠状病毒病(COVID-19)患者的疾病进程和死亡率。方法:分析了 211 例年龄在 60 岁及以上、诊断为 COVID-19 且肺部受累的患者的年龄、肺部受累程度、合并症和生化参数。研究了这些参数对 ICU 入院和死亡率的影响。结果:高龄、肺部受累严重程度、D-二聚体、铁蛋白和纤维蛋白原水平升高以及慢性阻塞性肺疾病(COPD)病史是预测 ICU 入院和死亡率的重要因素。除了高龄外,肺部受累严重程度和 COPD 病史对 COVID-19 病程中的死亡率有重大影响。

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