Ji Fangfei, Yang Yuexin, Xu Lei, Cai Jing, Ni Mingde, Wang Qiuzhen, Zhao Shanliang, Ma Aiguo
Department of Nutrition and Health, College of Public Health, Qingdao University, Qingdao, China.
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China.
J Hum Nutr Diet. 2022 Dec;35(6):1192-1201. doi: 10.1111/jhn.12985. Epub 2022 Jan 27.
The purpose of this study was to compare and evaluate the diet quality of tuberculosis patients and healthy adults by using the China Healthy Diet Index (CHDI) and to provide guidance for the diet of tuberculosis patients in the future.
A case-control study of 1241 patients and 1241 healthy individuals matchedfor sex and age. The CHDI was used to score the overall diet quality of patients in the casegroup and the control group.
The CHDI score of tuberculosis patients was 61.61 and that of healthy controls was 63.97. After adjustment for confounders, participants with >80 on CHDI were 73.5% less likely to develop tuberculosis than participants with <51 (OR: 0.265, 95% CI: 0.086, 0.813, p < 0.05). In the original model, the CHDI scores in the highest range were inversely associated with tuberculosis risk compared with the lowest range (OR: 0.687, 95% CI: 0.420,1.122, p < 0.001). After adjusting for confounders, the CHDI score was significantly associated with a reduced risk of tuberculosis (OR: 0.265, 95% CI: 0.086, 0.813, p < 0.001). After adjusting for confounders, a high-quality diet was positively correlated with anti-tuberculosis treatment outcomes (OR:0.957, 95% CI: 0.918,0.998, p = 0.039).
Compared with healthy adults, tuberculosis patients have poor diet quality with unreasonable diet structure. The insufficient intake of whole grains, vegetables, beans, aquatic products, meat and eggs and the excessive intake of pure energy food and solid fat suggests that the dietary structure of tuberculosis patients was unreasonable. This study provides an idea of the diet structure of tuberculosis patients.
本研究旨在运用中国健康饮食指数(CHDI)比较和评估结核病患者与健康成年人的饮食质量,为今后结核病患者的饮食提供指导。
一项病例对照研究,纳入1241例患者和1241名性别和年龄匹配的健康个体。采用CHDI对病例组和对照组患者的总体饮食质量进行评分。
结核病患者的CHDI评分为61.61,健康对照组为63.97。在对混杂因素进行调整后,CHDI评分>80的参与者患结核病的可能性比评分<51的参与者低73.5%(比值比:0.265,95%置信区间:0.086,0.813,p<0.05)。在原始模型中,与最低范围相比,最高范围的CHDI评分与结核病风险呈负相关(比值比:0.687,95%置信区间:0.420,1.122,p<0.001)。调整混杂因素后,CHDI评分与结核病风险降低显著相关(比值比:0.265,95%置信区间:0.086,0.813,p<0.001)。调整混杂因素后,高质量饮食与抗结核治疗效果呈正相关(比值比:0.957,95%置信区间:0.918,0.998,p=0.039)。
与健康成年人相比,结核病患者饮食质量较差,饮食结构不合理。全谷物、蔬菜、豆类、水产品、肉类和蛋类摄入不足,纯能量食物和固体脂肪摄入过多,提示结核病患者的饮食结构不合理。本研究为结核病患者的饮食结构提供了思路。