在浅表扩散性黑色素瘤内出现无黑色素性结节外观。

Amelanotic nodular appearance within superficial spreading melanoma.

机构信息

Bagcilar Research and Training Hospital, Department of Dermatology and Venereology, University of Health Sciences, Istanbul, Turkey.

Bagcilar Research and Training Hospital, Department of Nuclear Medicine, University of Health Sciences, Istanbul, Turkey.

出版信息

J Cosmet Dermatol. 2022 Sep;21(9):3949-3953. doi: 10.1111/jocd.14705. Epub 2021 Dec 27.

DOI:10.1111/jocd.14705

PMID:34962081

Abstract

Usual clinical types of malignant melanoma (MM) are lentigo maligna, superficial spreading, nodular, and acral lentiginous MMs. Rarer variants of MM are amelanotic, neurotropic, desmoplastic, metastatic, invisible, pedunculatedmelanoma (PM), or nodal melanoma (NM), which constitute less than 5% of cases. Recognition and discrimination of these variants are important to avoid misdiagnosis of MM. We report a 42-year-old Caucasian woman presented with a superficial spreading malignant melanoma (SSM) with an amelanotic nodular center. The lesion simulated a NM or PM clinically, but its histopathology showed an SSM. This misleading appearance of SSM has not been reported previously.

摘要

常见的恶性黑色素瘤（MM）临床类型包括：原位恶性黑色素瘤、浅表扩散型、结节型和肢端雀斑样黑色素瘤。MM 的罕见变异型包括无黑色素型、神经毒性型、促结缔组织增生型、转移性、隐匿性、有蒂黑色素瘤（PM）或淋巴结黑色素瘤（NM），这些变异型占病例的不到 5%。识别和区分这些变异型对于避免 MM 的误诊很重要。我们报告了一位 42 岁的白人女性，患有无黑色素性结节型浅表扩散型恶性黑色素瘤（SSM）。该病变在临床上模拟 NM 或 PM，但组织病理学显示为 SSM。SSM 具有这种误导性外观以前尚未报道过。