University Witten-Herdecke, Department of Obstetrics and Gynecology, Academic Hospital Cologne Weyertal University of Cologne, Germany.
Department of Obstetrics and Gynecology, University Witten-Herdecke, Marien-Hospital, Witten Marienplatz, 258452, Witten, Germany.
J Gynecol Obstet Hum Reprod. 2022 Feb;51(2):102303. doi: 10.1016/j.jogoh.2021.102303. Epub 2021 Dec 30.
Fibroids are the most common benign uterine tumors. Transcervical radiofrequency ablation with the Sonata® System offers a minimally invasive, incisionfree, organ-preserving therapy, with intraoperative visualization of fibroids using intrauterine ultrasound guidance. To demonstrate the effectiveness of transcervical radiofrequency ablation of fibroids that are 5 cm or larger using the Sonata® System, this retrospective analysis was collected.
151 patients have been treated with this method in our department up to the time of this analysis. Only patients with at least one fibroid of ≥5 cm and with bleeding symptoms, who were treated with the Sonata® System were included in this retrospective study. A total of 50 patients were included in the study and 57 fibroids were treated.
A total of 57 fibroids were detected and treated, however FIGO 1 and 2 fibroids (in total three fibroids were excluded). The smallest fibroid was 4 cm and the largest fibroid was 12 cm. A single ablation was performed in 18 cases, two ablation steps in 16 cases, three ablation steps in 13 cases, and more than three ablation steps in three cases. Depending on ablation steps, the shortest ablation time was 3 min 15 s and the longest ablation time was 25 min 6 s, with an average time of 9 min 12 s. 86% of patients reported an improvement of symptoms Conclusion: Thus, the Sonata® System is a simple, minimally invasive, rapid and successful method that shows significant improvement of symptoms even in large myomas from ≥5 cm.
子宫肌瘤是最常见的良性子宫肿瘤。Sonata®系统经宫颈射频消融术为一种微创、无切口、保留器官的治疗方法，术中使用宫内超声引导可视化子宫肌瘤。为了证明 Sonata®系统治疗 5cm 或更大的子宫肌瘤的有效性，进行了这项回顾性分析。
截至分析时，我院已采用该方法治疗了 151 例患者。本回顾性研究仅纳入了至少有一个≥5cm 的肌瘤且有出血症状、采用 Sonata®系统治疗的患者。共有 50 例患者纳入本研究，共治疗 57 个肌瘤。
共检测并治疗了 57 个肌瘤，但 FIGO 1 和 2 级肌瘤（总共排除了 3 个肌瘤）。最小肌瘤为 4cm，最大肌瘤为 12cm。18 例患者行单次消融，16 例患者行两次消融，13 例患者行三次消融，3 例患者行三次以上消融。根据消融步骤，最短消融时间为 3 分 15 秒，最长消融时间为 25 分 6 秒，平均时间为 9 分 12 秒。86%的患者报告症状改善。
因此，Sonata®系统是一种简单、微创、快速且成功的方法，即使对于≥5cm 的大肌瘤，也能显著改善症状。
