Department of Forensic Medicine and Toxicology, Faculty of Medicine, University of Colombo, Sri Lanka.
Instituto Nacional de Medicina Legal e Ciências Forenses, Coimbra, Portugal.
Pathologica. 2021 Dec;113(6):413-420. doi: 10.32074/1591-951X-254.
The COVID-19 pandemic is associated with a high case fatality rate in some countries even thought the majority of cases are asymptomatic. Scientific studies on this novel virus is limited and there is uncertainty regarding the best practices for death investigations both in terms of detection of the disease as well as autopsy safety. An online survey was conducted to identify how different institutions responded to the screening and management of dead bodies during the early phase of the pandemic from January to May. A questionnaire was developed using Google Forms and data was collected from 14 different forensic and pathological institutions in 9 countries. None of the institutions had performed any screening prior to March. Four institutions stated that screening was done routinely. In total, 322 cases had been screened using RT-PCR, out of which 40 positive cases were detected among four institutions. The commonest types of samples obtained were nasopharyngeal and oropharyngeal swabs which also had the highest rates of positivity followed by tracheal swab. Blood, swabs from cut surfaces of lung and lung tissue also gave positive results in some cases. Majority of the positive cases were > 65 years with a history suggestive of respiratory infection and were clinically suspected to have COVID-19 before death. Except for one institution which performed limited dissections, standard autopsies were conducted on all positive cases. Disposal of bodies involved the use of sealed body bags and labelling as COVID positive. Funeral rites were restricted and none of the institutions advocated cremation. There were no reports of disease transmission to those who handled COVID positive bodies.
新型冠状病毒肺炎(COVID-19)大流行在一些国家的病死率较高,尽管大多数病例为无症状。针对该新型病毒的科学研究有限,在检测疾病和尸检安全方面,对于死亡调查的最佳实践存在不确定性。本研究旨在通过在线调查,了解不同机构在 COVID-19 大流行早期(1 月至 5 月)对尸体的筛查和管理采取了哪些措施。采用 Google Forms 开发了问卷,并从 9 个国家的 14 个不同法医和病理机构收集数据。在 3 月之前,没有任何机构进行任何筛查。有 4 家机构表示常规进行筛查。共对 322 例病例进行了 RT-PCR 检测,其中 4 家机构检测出 40 例阳性病例。最常见的标本类型为鼻咽和口咽拭子,其阳性率最高,其次为气管拭子。在一些病例中,血液、肺切面上的拭子和肺组织也有阳性结果。大多数阳性病例为年龄 > 65 岁,有呼吸道感染史,生前临床疑似 COVID-19。除一家机构进行了有限的解剖外,所有阳性病例均进行了标准尸检。尸体的处理包括使用密封尸袋并贴上 COVID 阳性标签。葬礼受到限制,没有一家机构提倡火化。处理 COVID 阳性尸体的人员未报告发生疾病传播。