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热灌注化疗后阴囊坏死:病例报告及文献复习

Scrotal Necrosis Following Heated Intra-peritoneal Chemotherapy: Case Report and Review of the Literature.

作者信息

Fagih Samiha N, Baghdadi Rana M, Banjer Aeshah Y, Ismail Amal A, Addas Majda A, Shabkah Alaa A, Trabulsi Nora H

机构信息

Department of Surgery, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.

Department of Surgery, International Medical Center, Jeddah, SAU.

出版信息

Cureus. 2021 Dec 23;13(12):e20638. doi: 10.7759/cureus.20638. eCollection 2021 Dec.

Abstract

Scrotal necrosis is a rare occurrence that is scarcely reported among patients having undergone heated intra-peritoneal chemotherapy (HIPEC) procedures. Due to anatomic factors and the thermally enhanced cytotoxicity of chemotherapeutic agents, this complication can have debilitating post-operative effects. We herein highlight the presentation of scrotal necrosis in a patient who underwent HIPEC procedure for peritoneal metastasis secondary to colorectal carcinoma, and how it contrasts to previously documented cases of a similar nature. Furthermore, we describe a successful management strategy that consisted of conservative measures followed by surgical debridement and primary repair, and enabled the patient to experience significant functional and cosmetic improvement.

摘要

阴囊坏死是一种罕见的情况,在接受热腹腔内化疗(HIPEC)手术的患者中鲜有报道。由于解剖因素以及化疗药物热增强的细胞毒性,这种并发症可能会产生严重的术后影响。在此,我们重点介绍一名因结直肠癌继发腹膜转移而接受HIPEC手术的患者出现阴囊坏死的情况,以及它与先前记录的类似性质病例的对比。此外,我们描述了一种成功的治疗策略,该策略包括保守措施,随后进行手术清创和一期修复,使患者在功能和外观上都有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f40/8712224/f4682780dfab/cureus-0013-00000020638-i01.jpg

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